USP9X binds Ub:PEX5S

Stable Identifier
R-HSA-9033526
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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The deubiquitinating enzyme USP9X binds cytosolic ubiquitinated PEX5S (Ub:PEX5S) and then hydrolyzes the thioester bond between the carboxyl terminus of ubiquitin and cysteine-11 of PEX5S (inferred from the large isoform of PEX5 in Grou et al. 2012).

Literature References
PubMed ID Title Journal Year
22371489 Identification of ubiquitin-specific protease 9X (USP9X) as a deubiquitinase acting on ubiquitin-peroxin 5 (PEX5) thioester conjugate

Grou, CP, Francisco, T, Rodrigues, TA, Freitas, MO, Pinto, MP, Carvalho, AF, Domingues, P, Wood, SA, Rodríguez-Borges, JE, Sá-Miranda, C, Fransen, M, Azevedo, JE

J. Biol. Chem. 2012
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