NTRK2 promotes TIAM1 phosphorylation

Stable Identifier
R-HSA-9033284
Type
Reaction [uncertain]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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General
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Upon binding to NTRK2 (TRKB), TIAM1 is phosphorylated at tyrosine residue Y829, presumably by NTRK2, but this has not been shown directly (Lai et al. 2012).
Participants
Participates
Catalyst Activity

protein tyrosine kinase activity of BDNF:p-5Y,S479-NTRK2 homodimer:TIAM1 [plasma membrane]

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