RUNX2 binds to SATB2

Stable Identifier
R-HSA-8985275
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Based on studies in mice, RUNX2 forms a complex with the transcription factor SATB2. SATB2 may promote transcription of RUNX2 targets, including osteocalcin (BGLAP) (Dobreva et al. 2006).
Literature References
PubMed ID Title Journal Year
16751105 SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation

Chahrour, M, Chirivella, L, FariƱas, I, Karsenty, G, Kanzler, B, Dobreva, G, Dautzenberg, M, Grosschedl, R

Cell 2006
Participants
Participates
Inferred From
Authored
Reviewed
Created
Cite Us!