Reactome | p-NUCB1 [endoplasmic reticulum lumen]

p-NUCB1 [endoplasmic reticulum lumen]

Stable Identifier

R-HSA-8957027

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen

Synonyms

NUCB1, Nucleobindin-1, NUCB1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q02818 NUCB1

Gene Names

NUCB1, NUC

Chain

signal peptide:1-26, chain:27-461

Reference Genes

BioGPS Gene:4924 NUCB1

COSMIC (genes):NUCB1 NUCB1

CTD Gene:4924 NUCB1

dbSNP Gene:4924 NUCB1

ENSEMBL:ENSG00000104805 NUCB1

ENSEMBL_homo_sapiens_GENE:ENSG00000104805.17 NUCB1

HGNC:8043 NUCB1

KEGG Gene (Homo sapiens):4924 NUCB1

Monarch:4924 NUCB1

NCBI Gene:4924 NUCB1

OMIM:601323 NUCB1

UCSC:Q02818 NUCB1

Reference Transcript

Other Identifiers

11751049_a_at

11751050_x_at

11755969_a_at

16863884

200646_PM_s_at

200646_s_at

200649_PM_at

200649_at

3838018

3838020

3838021

3838023

3838024

3838025

3838026

3838029

3838030

3838031

3838033

3838035

3838036

3838038

3838039

3838041

3838042

3838043

3838044

3838045

3838047

40817_at

4924

8030133

A_23_P78771

GE58173

GE81604

GO:0001965

GO:0003677

GO:0005085

GO:0005509

GO:0005515

GO:0005576

GO:0005615

GO:0005737

GO:0005783

GO:0005788

GO:0005793

GO:0005794

GO:0007264

GO:0016020

GO:0023052

GO:0043226

GO:0046872

GO:0070062

GO:0098772

HMNXSV003019333

ILMN_1722634

PH_hs_0010324

TC19000712.hg

U31342_at

g12803104_3p_at

g5453817_3p_a_at

Participates

as a member of

FAM20C products [endoplasmic reticulum lumen] (Homo sapiens)

Other forms of this molecule

NUCB1 [endoplasmic reticulum lumen]

Inferred To

phospho-p-NUCB1 [endoplasmic reticulum lumen] (Mus musculus)

phospho-p-NUCB1 [endoplasmic reticulum lumen] (Rattus norvegicus)

phospho-nucb-1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)

phospho-NUCB1 [endoplasmic reticulum lumen] (Bos taurus)

phospho-NUCB1 [endoplasmic reticulum lumen] (Canis familiaris)

phospho-NUCB1 [endoplasmic reticulum lumen] (Drosophila melanogaster)

phospho-NUCB1 [endoplasmic reticulum lumen] (Sus scrofa)

phospho-nucb1 [endoplasmic reticulum lumen] (Xenopus tropicalis)

Modified Residues

Name

phosphorylated residue at unknown position

PsiMod Name

phosphorylated residue [MOD:00696]

PsiMod Definition

A protein modification that effectively replaces a hydrogen atom with a phosphate group.

Cross References

RefSeq

NP_006175.2, XP_016882334.1

Guide to Pharmacology - Targets

2871

OpenTargets

ENSG00000104805

HPA

ENSG00000104805-NUCB1

GeneCards

Q02818

Ensembl

ENST00000407032, ENSP00000385923, ENST00000405315, ENSP00000385211, ENSG00000104805

PRO

Q02818

Pharos - Targets

Q02818

HMDB Protein

HMDBP07855

PDB

1SNL

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P05067 APP	20	APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136) APP-C99 [cytosol] (R-HSA-9617603) APP(18-770) [extracellular region] (R-HSA-49335) APP(18-770) [platelet alpha granule lumen] (R-HSA-139835) APP(18-687) [extracellular region] (R-HSA-9010033) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(18-770) [Golgi lumen] (R-HSA-8871509) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-671) [endosome lumen] (R-HSA-5693003) APP(714-770) [endosome lumen] (R-HSA-6783325) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(18-770) [endosome lumen] (R-HSA-5229077) p-APP [endoplasmic reticulum lumen] (R-HSA-8957012) APP [endoplasmic reticulum lumen] (R-HSA-8956696) APP(672-711) [extracellular region] (R-HSA-976740) APP(672-711) [cytosol] (R-HSA-877188) APP(672-713) [extracellular region] (R-HSA-879340)	0.556	3
UniProt:P10823	5	GNAT1 (Met removed) [cytosol] (R-SCE-2534043) GNAT1 [cytosol] (R-SCE-2565915) N-(C14:0)-GNAT1 [photoreceptor disc membrane] (R-SCE-2534062) GNAZ [plasma membrane] (R-SCE-167416) GNAI3 [plasma membrane] (R-SCE-55365)	0.556	3

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