RUNX2 binds tyrosine phosphorylated YAP1

Stable Identifier
R-HSA-8937864
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Based on studies in rat, RUNX2, presumably associated with CBFB, binds YAP1, phosphorylated on an unknown tyrosine residue by SRC and/or YES1. The interaction involves the PY motif of RUNX2 (Zaidi et al. 2004).

Literature References
PubMed ID Title Journal Year
14765127 Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription

Zaidi, SK, Sullivan, AJ, Medina, R, Ito, Y, van Wijnen, AJ, Stein, JL, Lian, JB, Stein, GS

EMBO J. 2004
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