RUNX3 binds the JAG1 gene promoter

Stable Identifier
R-HSA-8878193
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
RUNX3 binds the promoter of the JAG1 gene, which encodes a ligand for NOTCH receptors (Nishina et al. 2011).
Literature References
PubMed ID Title Journal Year
21637926 Restored expression of the tumor suppressor gene RUNX3 reduces cancer stem cells in hepatocellular carcinoma by suppressing Jagged1-Notch signaling

Nakanishi, Y, Matsubara, M, Iwamuro, M, Yagi, T, Tanaka, S, Yamamoto, K, Uemura, M, Kataoka, J, Takaoka, N, Shiraha, H, Horiguchi, S, Nishina, S

Oncol. Rep. 2011
Participants
Participates
Authored
Reviewed
Created
Cite Us!