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GNAS [plasma membrane]
Stable Identifier
R-HSA-8873941
Type
Set [CandidateSet]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
G alpha (s), Gs
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Parasitic Infection Pathways (Homo sapiens)
Leishmania infection (Homo sapiens)
Leishmania parasite growth and survival (Homo sapiens)
Anti-inflammatory response favouring Leishmania parasite infection (Homo sapiens)
ADORA2B mediated anti-inflammatory cytokines production (Homo sapiens)
ADORA2B (in Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs) exchanges GDP for GTP on Gs (Homo sapiens)
ADORA2B:Ade-Rib:Heterotrimeric G-protein Gs:GTP [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs:GDP [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
G alpha (s):GDP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
ADORA2B:Ade-Rib binds heterometric G-protein Gs (Homo sapiens)
Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs:GDP [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
G alpha (s):GDP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
G alpha (s):GDP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
ADORA2B:Ade-Rib:GsGTP dissociates (Homo sapiens)
ADORA2B:Ade-Rib:Heterotrimeric G-protein Gs:GTP [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate (Homo sapiens)
G alpha (s):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
G alpha (s) activates adenylate cyclase (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
G alpha (s):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
Hemostasis (Homo sapiens)
Platelet homeostasis (Homo sapiens)
Prostacyclin signalling through prostacyclin receptor (Homo sapiens)
Activated prostacyclin receptor binds G-protein Gs (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
G alpha (s):GDP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
Prostacyclin:prostacyclin receptor:Gs (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
G alpha (s):GDP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
Dissociation of the Prostacyclin receptor:Gs complex (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
Prostacyclin:prostacyclin receptor:G-protein Gs (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
Gs activation by prostacyclin receptor (Homo sapiens)
Prostacyclin:prostacyclin receptor:G-protein Gs (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
Prostacyclin:prostacyclin receptor:Gs (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
G alpha (s):GDP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
Metabolism (Homo sapiens)
Integration of energy metabolism (Homo sapiens)
Glucagon signaling in metabolic regulation (Homo sapiens)
G alpha (s) activates adenylate cyclase (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
G alpha (s):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
G(s):GTP activates Adenylyl cyclase (Homo sapiens)
ADCY5,6,8:G-alpha(s):GTP [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
Glucagon:GCGR mediates GTP-GDP exchange (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
G-protein with G(s) alpha:GDP [plasma membrane] (Homo sapiens)
G alpha (s):GDP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
PKA activation in glucagon signalling (Homo sapiens)
Activated Adenylate cyclase catalyses cAMP synthesis (Homo sapiens)
G alpha (s):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
Regulation of insulin secretion (Homo sapiens)
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Homo sapiens)
Activated Adenylyl cyclase synthesizes cyclic AMP (Homo sapiens)
ADCY5,6,8:G-alpha(s):GTP [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
G(s):GTP activates Adenylyl cyclase (Homo sapiens)
ADCY5,6,8:G-alpha(s):GTP [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
GLP1R binds GLP1 (Homo sapiens)
GLP1:GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Homo sapiens)
G alpha (s):GDP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Homo sapiens)
G alpha (s):GDP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
GLP1R binds GLP1R agonists (Homo sapiens)
GLP1R:GLP1R agonists [plasma membrane] (Homo sapiens)
GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Homo sapiens)
G alpha (s):GDP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Homo sapiens)
G alpha (s):GDP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
GLP1R:GLP1 activates G(s) (Homo sapiens)
GLP-1:GLP-1R:Heterotrimeric G(s):GTP [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
GLP1:GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Homo sapiens)
G alpha (s):GDP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
Heterotrimeric G(s) complex dissociates (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
G-alpha(s):GTP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate (Homo sapiens)
G alpha (s):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
G alpha (s) signalling events (Homo sapiens)
Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate (Homo sapiens)
G alpha (s):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
G alpha (s) activates adenylate cyclase (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
G alpha (s):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
G alpha (s) auto-inactivates by hydrolysing GTP to GDP (Homo sapiens)
G alpha (s):GDP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
G alpha (s):GTP:SRC catalyzes SRC to p-Y419-SRC (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
G alpha (s):GTP:SRC [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
G alpha (s):GTP:p-Y419-SRC [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
G alpha (s):GTP:SRC dissociates (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
G alpha (s):GTP:p-Y419-SRC [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
G protein alpha (s):GTP binds SRC (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
G alpha (s):GTP:SRC [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
GPER1 signaling (Homo sapiens)
Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate (Homo sapiens)
G alpha (s):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s (Homo sapiens)
GPER1:Heterotrimeric G-protein Gs (active):ESTG [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
GPER1:Heterotrimeric G-protein Gs:ESTG [plasma membrane] (Homo sapiens)
GPER1:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
G alpha (s):GDP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
ESTG-stimulated dissociation of GPER:heterotrimeric G-protein (s) complex (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
GPER1:Heterotrimeric G-protein Gs (active):ESTG [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
G alpha (s) activates adenylate cyclase (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
G alpha (s):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
GPER:Heterotrimeric G-protein Gs binds ESTG (Homo sapiens)
GPER1:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
G alpha (s):GDP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
GPER1:Heterotrimeric G-protein Gs:ESTG [plasma membrane] (Homo sapiens)
GPER1:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
G alpha (s):GDP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
Inactive G alpha (s) reassociates with G beta:gamma (Homo sapiens)
G alpha (s):GDP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
G alpha (s):GDP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
Liganded Gs-activating GPCR acts as a GEF for Gs (Homo sapiens)
Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs:GDP [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
G alpha (s):GDP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
G alpha (s):GDP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
G alpha (s):GDP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
G alpha (s):GDP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gs complex dissociates (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
G alpha (z) signalling events (Homo sapiens)
Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate (Homo sapiens)
G alpha (s):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class B/2 (Secretin family receptors) (Homo sapiens)
Glucagon-type ligand receptors (Homo sapiens)
GLP1R binds GLP1 (Homo sapiens)
GLP1:GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Homo sapiens)
G alpha (s):GDP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Homo sapiens)
G alpha (s):GDP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
Signaling by Hedgehog (Homo sapiens)
Hedgehog 'off' state (Homo sapiens)
GPR161 promotes cAMP production in a G alpha(s)-dependent manner (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
Aquaporin-mediated transport (Homo sapiens)
Vasopressin regulates renal water homeostasis via Aquaporins (Homo sapiens)
AVP:AVPR2 Complex binds inactive heterotrimeric G(s) complex (Homo sapiens)
AVPR2:AVP:G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
G alpha (s):GDP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
G alpha (s):GDP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Homo sapiens)
AVPR2:AVP:G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
G alpha (s):GDP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
AVPR2:AVP:G-alpha(s):GTP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
G-alpha(s):GTP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
Activated Adenylate cyclase catalyses cAMP synthesis (Homo sapiens)
G alpha (s):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
G alpha (s) activates adenylate cyclase (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
G alpha (s):GTP:Adenylate cyclase [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
Heterotrimeric G(s) complex dissociates (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
G-alpha(s):GTP:G-beta:G-gamma [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
GNAS [plasma membrane] (Homo sapiens)
Participants
members
GNAS2 [plasma membrane]
(Homo sapiens)
candidates
GNAS1 [plasma membrane]
(Homo sapiens)
Participates
as a component of
G alpha (s):GDP [plasma membrane] (Homo sapiens)
G alpha (s):GTP [plasma membrane] (Homo sapiens)
Inferred To
GNAS [plasma membrane]
(Caenorhabditis elegans)
GNAS [plasma membrane]
(Canis familiaris)
GNAS [plasma membrane]
(Drosophila melanogaster)
GNAS [plasma membrane]
(Gallus gallus)
GNAS [plasma membrane]
(Mus musculus)
GNAS [plasma membrane]
(Rattus norvegicus)
GNAS [plasma membrane]
(Sus scrofa)
Ghost homologue of GNAS [plasma membrane]
(Bos taurus)
Ghost homologue of GNAS [plasma membrane]
(Danio rerio)
Ghost homologue of GNAS [plasma membrane]
(Xenopus tropicalis)
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