OTUD7A hydrolyses K11diUb

Stable Identifier
R-HSA-8865182
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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OTU domain-containing protein 7A (CEZANNE2, OTUD7A ) has deubiquitinating activity that is specific for Lys11 ubiquitin linkages (Mevissen et al 2013).

Literature References
PubMed ID Title Journal Year
23827681 OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis

Mevissen, TE, Hospenthal, MK, Geurink, PP, Elliott, PR, Akutsu, M, Arnaudo, N, Ekkebus, R, Kulathu, Y, Wauer, T, El Oualid, F, Freund, SM, Ovaa, H, Komander, D

Cell 2013
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
thiol-dependent ubiquitinyl hydrolase activity of OTUD7A [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created