Reactome | RELN:VLDLR:DAB1 binds SH3KBP1

RELN:VLDLR:DAB1 binds SH3KBP1

Stable Identifier

R-HSA-8855259

Type

Reaction [binding]

Species

Homo sapiens

Compartment

cytosol, extracellular region, plasma membrane

ReviewStatus

5/5

Locations in the PathwayBrowser

Expand all

General

SBML | | PDF

SVG | | PPTX | SBGN

Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

SH3 domain-containing kinase-binding protein 1 (SH3KBP1, aka CIN85) is an adapter protein involved in the regulation of endocytosis and lysosomal degradation of ligand-induced receptor tyrosine kinases (Fuchigami et al. 2013).

Literature References

PubMed ID	Title	Journal	Year
23506116	Dab1-mediated colocalization of multi-adaptor protein CIN85 with Reelin receptors, ApoER2 and VLDLR, in neurons Hisanaga, S, Fukuda, M, Tomita, Y, Hattori, M, Tsuchiya, Y, Nakajima, K, Takano, T, Sato, Y, Saito, T, Kubo, K, Fuchigami, T, Miyauchi, SY	Genes Cells	2013