Reactome | p-Y-KHDRSB3 [nucleoplasm]

p-Y-KHDRSB3 [nucleoplasm]

Stable Identifier

R-HSA-8849035

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

p-Y-SLM2

Locations in the PathwayBrowser for interactor UniProt:Q9NQL9 DMRT3

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External Reference Information

External Reference

UniProt:O75525 KHDRBS3

Gene Names

KHDRBS3, SALP, SLM2

Chain

chain:1-346

Reference Genes

BioGPS Gene:10656 KHDRBS3

COSMIC (genes):KHDRBS3 KHDRBS3

CTD Gene:10656 KHDRBS3

dbSNP Gene:10656 KHDRBS3

ENSEMBL:ENSG00000131773 KHDRBS3

HGNC:18117 KHDRBS3

KEGG Gene (Homo sapiens):10656 KHDRBS3

Monarch:10656 KHDRBS3

NCBI Gene:10656 KHDRBS3

OMIM:610421 KHDRBS3

UCSC:O75525 KHDRBS3

Reference Transcript

RefSeq:NM_006558.2 KHDRBS3

Other Identifiers

0005550452

10656

11732318_a_at

11744581_a_at

17072979

209781_s_at

275

3117383

3117385

3117386

3117387

3117388

3117399

3117400

3117403

3117404

3117406

3117412

3117420

3117431

3117432

3117433

3117434

3117435

3117436

3117437

31786_at

500

5EL3

5ELR

5ELS

5ELT

5EMO

8148448

981

A_14_P114504

A_23_P257335

A_33_P3332081

A_33_P3394727

AAC24857

AAC99294

AAC99295

AAH32606

AAH68536

AF051321

AF051322

AF069681

BC032606

BC068536

CCDS6374

E5RG12

E5RHD3

E5RJZ9

ENSG00000131773

ENSP00000348108

ENST00000355849

ENST00000355849.9

EntrezGene:10656

EntrezGene:KHDRBS3

g3273831_3p_a_at

GE54435

GO:0003674

GO:0003676

GO:0003723

GO:0005515

GO:0005575

GO:0005622

GO:0005623

GO:0005634

GO:0005654

GO:0006397

GO:0008150

GO:0017124

GO:0019904

GO:0022607

GO:0034641

GO:0042802

GO:0043226

GO:0048024

GO:0051259

GO:0065003

HGNC:18117

HPA000275

HPA000500

HPA000981

Hs.13565.1.A1_3p_at

ILMN_1691747

ILMN_1727790

IPR004087

IPR004088

IPR032335

IPR032571

IPR036612

KHDRBS3

KHDRBS3-201

MIM:610421

NM_006558

NP_006549

PF00013

PF16274

PF16568

PH_hs_0001310

SM00322

TC08000778.hg

UPI0000073E6F

XM_005250757

XM_005250758

XM_011516796

XM_011516797

XM_011516798

XM_024447053

XP_005250814

XP_005250815

XP_011515098

XP_011515099

XP_011515100

XP_024302821

XR_001745455

XR_242372

XR_242374

Participant Of

output

PTK6 phosphorylates KHDRBS3

Other forms of this molecule

KHDRSB3 [nucleoplasm]

Inferred To

Homologues of p-Y-KHDRSB3 [nucleoplasm] (Drosophila melanogaster)

phospho-p-Y-KHDRSB3 [nucleoplasm] (Bos taurus)

phospho-p-Y-KHDRSB3 [nucleoplasm] (Caenorhabditis elegans)

phospho-p-Y-KHDRSB3 [nucleoplasm] (Canis familiaris)

phospho-p-Y-KHDRSB3 [nucleoplasm] (Danio rerio)

phospho-p-Y-KHDRSB3 [nucleoplasm] (Drosophila melanogaster)

phospho-p-Y-KHDRSB3 [nucleoplasm] (Gallus gallus)

phospho-p-Y-KHDRSB3 [nucleoplasm] (Mus musculus)

phospho-p-Y-KHDRSB3 [nucleoplasm] (Rattus norvegicus)

phospho-p-Y-KHDRSB3 [nucleoplasm] (Sus scrofa)

phospho-p-Y-KHDRSB3 [nucleoplasm] (Xenopus tropicalis)

Modified Residues

Name

O4'-phospho-L-tyrosine at unknown position

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

NP_006549.1

OpenTargets

ENSG00000131773

GeneCards

O75525

PRO

O75525

PDB

5EMO, 5ELT, 5ELR, 5ELS, 5EL3

Interactors (43)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8WWY3 PRPF31	1	PRPF31 [nucleoplasm] (R-HSA-6806772)	0.718	6
UniProt:Q96MU7 YTDC1			0.696	5
UniProt:Q8TBE0 BAHD1			0.666	4
UniProt:P38159 RBMX	1	RBMX [nucleoplasm] (R-HSA-71939)	0.621	3
UniProt:Q9H9D4 ZN408			0.621	3
UniProt:Q5VWX1 KHDRBS2	2	p-Y-KHDRBS2 [nucleoplasm] (R-HSA-8849031) KHDRBS2 [nucleoplasm] (R-HSA-8849028)	0.621	3
UniProt:Q92835 INPP5D	1	INPP5D [cytosol] (R-HSA-197940)	0.556	3
UniProt:Q6IPE9 Q6IPE9			0.556	3
UniProt:Q9NQL9 DMRT3			0.556	3
UniProt:P38340 NTM1			0.556	3
IntAct:EBI-10188384 57727			0.556	3
UniProt:A0A0S2Z5X4 A0A0S2Z5X4			0.556	3
UniProt:Q07666 KHDRBS1	3	p-Y435,Y440,Y443-KHDRBS1 [cytosol] (R-HSA-8848995) p-Y435,Y440,Y443-KHDRBS1 [nucleoplasm] (R-HSA-8848970) KHDRBS1 [nucleoplasm] (R-HSA-8848941)	0.553	2
UniProt:O75525 KHDRBS3	2	p-Y-KHDRSB3 [nucleoplasm] (R-HSA-8849035) KHDRSB3 [nucleoplasm] (R-HSA-8849040)	0.553	2
UniProt:Q9Y580 RBM7			0.553	2
UniProt:Q8N5R6 CCD33			0.553	2
UniProt:P61978 HNRNPK	2	SUMO2-K422-HNRNPK [nucleoplasm] (R-HSA-4570532) HNRNPK [nucleoplasm] (R-HSA-71945)	0.553	2
UniProt:Q8WX92 NELFB	3	NELFB [cytosol] (R-HSA-9603526) NELFB [mitochondrial outer membrane] (R-HSA-9603553) NELFB [nucleoplasm] (R-HSA-112427)	0.524	2
UniProt:Q9Y272 RASD1			0.488	2
UniProt:Q9Y5E9 PCDBE			0.488	2
UniProt:Q86VE0 MYPOP			0.488	2
UniProt:Q8NE01 CNNM3			0.488	2
UniProt:Q8IVT4 Q8IVT4			0.488	2
UniProt:P29972 AQP1	1	AQP1 [plasma membrane] (R-HSA-431700)	0.488	2
UniProt:Q9UK33 ZN580			0.488	2
UniProt:P40938 RFC3	1	RFC3 [nucleoplasm] (R-HSA-68431)	0.488	2
UniProt:Q96RF0 SNX18	1	SNX18 [cytosol] (R-HSA-8868038)	0.488	2
UniProt:P98179 RBM3			0.488	2
UniProt:P61978-2 HNRNPK			0.488	2
UniProt:Q6U949 IG2AS			0.488	2
UniProt:Q86XF7 ZN575			0.488	2
UniProt:A0A090N7T1 A0A090N7T1			0.488	2
UniProt:Q9UNE2 RPH3L			0.488	2
UniProt:Q3SY00 T10IP			0.488	2
UniProt:P25786 PSMA1	2	PSMA1 [cytosol] (R-HSA-68724) PSMA1 [nucleoplasm] (R-HSA-174333)	0.488	2
UniProt:Q8IXW0 LMTD2			0.488	2
UniProt:Q92835-2 INPP5D			0.488	2
UniProt:Q86YV0 RASAL3	1	RASAL3 [cytosol] (R-HSA-5658226)	0.488	2
UniProt:P79522 PRR3			0.488	2
UniProt:Q5BKZ1 ZN326			0.488	2
UniProt:P29597 TYK2	5	p-Y-TYK2 [cytosol] (R-HSA-6784366) p-TYK2 [cytosol] (R-HSA-8950424) TYK2 [cytosol] (R-HSA-877348) p-Y1054,Y1055-TYK2 [cytosol] (R-HSA-909682) p-Y1054-TYK2 [cytosol] (R-HSA-1112598)	0.488	2
UniProt:Q92608 DOCK2	3	DOCK2 [extracellular region] (R-HSA-6806310) DOCK2 [specific granule lumen] (R-HSA-6799558) DOCK2 [cytosol] (R-HSA-200938)	0.488	2
UniProt:P02008 HBAZ			0.488	2