ATP binds to P2X7

Stable Identifier
R-HSA-877178
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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P2X7 is a receptor for extracellular ATP that acts as a ligand gated non-selective cation channel. It is also responsible for the ATP-dependent lysis of macrophages, which it brings about by mediating the formation of membrane pores permeable to large molecules (Adinolfi et al. 2005).

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