Reactome | mRNP complex dissociates from cytosolic face of NPC

mRNP complex dissociates from cytosolic face of NPC

Stable Identifier

R-HSA-75098

Type

Reaction [dissociation]

Species

Homo sapiens

Compartment

cytosol, nuclear envelope

Synonyms

Release from the NPC and Disassembly of the mRNP

ReviewStatus

5/5

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mRNP complex dissociates from cytosolic face of NPC

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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

At the beginning of this reaction, 1 molecule of and 1 molecule of 'Export Receptor bound mature mRNA Complex' are present. At the end of this reaction, 1 molecule of 'THOC4(Aly/Ref)', 1 molecule of 'Mature mRNP Complex', 1 molecule of 'SRm160', and 1 molecule of 'TAP' are present.

This reaction takes place in the 'cytoplasm'.

Literature References

PubMed ID	Title	Journal	Year
18423201	SKAR links pre-mRNA splicing to mTOR/S6K1-mediated enhanced translation efficiency of spliced mRNAs Jülich, K, Ma, XM, Blenis, J, Richardson, CJ, Yoon, SO	Cell	2008
12093754	The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling Maquat, LE, Lejeune, F, Ishigaki, Y, Li, X	EMBO J.	2002