DHODH [mitochondrial inner membrane]

Stable Identifier
R-HSA-73523
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
dihydroorotate dehydrogenase, Dihydroorotate dehydrogenase, mitochondrial precursor (EC 1.3.3.1) (Dihydroorotate oxidase) (DHOdehase) (Fragment), Dihydroorotate dehydrogenase, mitochondrial precursor , Dihydroorotate oxidase, DHOdehase
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
10889450 Indirect inhibition of mitochondrial dihydroorotate dehydrogenase activity by nitric oxide.

Beuneu, C, Auger, R, Löffler, M, Lepoivre, M, Guissani, A, Lemaire, G

Free Radic Biol Med 2000
9693067 Expression, purification, and characterization of histidine-tagged rat and human flavoenzyme dihydroorotate dehydrogenase.

Knecht, W, Fries, M, Bader, B, Löffler, M

Protein Expr Purif 1998
165196 Superoxide production and electron transport in mitochondrial oxidation of dihydroorotic acid.

Forman, JH, Kennedy, J

J Biol Chem 1975
External Reference Information
External Reference
Gene Names
DHODH
Chain
chain:1-395, transit peptide:1-10
Reference Transcript
Other Identifiers
11743643_a_at
16820927
1723
213632_PM_at
213632_at
217647_PM_at
217647_at
33195_at
3667813
3667818
3667821
3667824
3667828
3667830
3667834
3667835
3667836
3667837
3667840
3667841
3667842
3667843
3667845
3667846
3667847
3667849
3667851
71779_at
7997179
A_23_P15202
GE58156
GO:0003824
GO:0004151
GO:0004152
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005739
GO:0005743
GO:0005829
GO:0006207
GO:0006221
GO:0006225
GO:0009220
GO:0016020
GO:0016491
GO:0016627
GO:0016787
GO:0043226
GO:0044205
GO:0055086
GO:0106430
GO:1901135
HMNXSV003036391
Hs.283729.0.A1_3p_at
Hs.283729.0.A1_3p_x_at
Hs.94925.0.S1_3p_at
Hs.94925.0.S2_3p_s_at
ILMN_1782993
ILMN_2381206
M94065_at
PH_hs_0024658
PH_hs_0040315
TC16000599.hg
Participates
Inferred To
Cross References
RefSeq
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC target
ZINC - Biogenic
PRO
ZINC - Investigational
IntEnz
GeneCards
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (1)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P49638 TTPA  1 0.556 3
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