GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal

Stable Identifier
R-HSA-70361
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
Synonyms
alpha-D-galactose 1-phosphate + UDP-alpha-D_glucose <=> alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose
ReviewStatus
5/5
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GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal
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Cytosolic galactose-1-phosphate uridylyltransferase (GALT) catalyzes the reaction of alpha-D-galactose 1-phosphate and UDP glucose to form D-glucose 1-phosphate and UDP galactose (Reichardt & Woo 1991).
Literature References
Participants
Input
Output
Participates
as an event of
Catalyst Activity

UDP-glucose:hexose-1-phosphate uridylyltransferase activity of GALT [cytosol]

Physical Entity
GALT [cytosol] (Homo sapiens)
Activity
UDP-glucose:hexose-1-phosphate uridylyltransferase activity (GO:0008108)
Orthologous Events
GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal (Bos taurus)
GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal (Caenorhabditis elegans)
GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal (Canis familiaris)
GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal (Drosophila melanogaster)
GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal (Gallus gallus)
GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal (Mus musculus)
GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal (Rattus norvegicus)
GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal (Sus scrofa)
Cross References
RHEA
Authored
Reviewed
D'Eustachio, P  (2025-01-23)
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