Formation of Cyclin E:Cdk2 complexes

Stable Identifier
R-HSA-69191
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The E-type cyclins and Cyclin Dependent Kinase 2 control the transition from G1 to S phase. Cdk2 is competent to carry out the necessary reactions only when complexed with Cyclin E.
Literature References
PubMed ID Title Journal Year
7799941 Effects of phosphorylation by CAK on cyclin binding by CDC2 and CDK2.

Wessling, HC, Desai, D, Fisher, RP, Morgan, DO

Mol Cell Biol 1995
Participants
Participates
Orthologous Events
Cite Us!