Reactome | p-S15,S33,S46-TP53 Tetramer [nucleoplasm]

p-S15,S33,S46-TP53 Tetramer [nucleoplasm]

Stable Identifier

R-HSA-6805275

Type

Complex

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser

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Gene expression (Transcription) (Homo sapiens)

- RNA Polymerase II Transcription (Homo sapiens)
  - Generic Transcription Pathway (Homo sapiens)
    - Transcriptional Regulation by TP53 (Homo sapiens)
      - Regulation of TP53 Activity (Homo sapiens)
        
        Regulation of TP53 Activity through Phosphorylation (Homo sapiens)
        
        CDK5 phosphorylates TP53 (Homo sapiens)
        
        p-S15,S33,S46-TP53 Tetramer [nucleoplasm] (Homo sapiens)

Literature References

PubMed ID	Title	Journal	Year
17591690	Stabilization and activation of p53 induced by Cdk5 contributes to neuronal cell death Kim, HS, Lee, SJ, Lee, JH, Kim, KT	J. Cell. Sci.	2007

Participants

components

x 4 p-S15,S33,S46-TP53 [nucleoplasm] (Homo sapiens)

Participates

as an output of

CDK5 phosphorylates TP53 (Homo sapiens)

Inferred To

p-S15,S33,S46-TP53 Tetramer [nucleoplasm] (Bos taurus)

p-S15,S33,S46-TP53 Tetramer [nucleoplasm] (Canis familiaris)

p-S15,S33,S46-TP53 Tetramer [nucleoplasm] (Danio rerio)

p-S15,S33,S46-TP53 Tetramer [nucleoplasm] (Drosophila melanogaster)

p-S15,S33,S46-TP53 Tetramer [nucleoplasm] (Mus musculus)

p-S15,S33,S46-TP53 Tetramer [nucleoplasm] (Rattus norvegicus)

p-S15,S33,S46-TP53 Tetramer [nucleoplasm] (Sus scrofa)

p-S15,S33,S46-TP53 Tetramer [nucleoplasm] (Xenopus tropicalis)

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