Reactome | p-S15,S20,Me-R333,Me2-R335,R337-TP53 Tetramer [nucleoplasm]

p-S15,S20,Me-R333,Me2-R335,R337-TP53 Tetramer [nucleoplasm]

Stable Identifier

R-HSA-6804382

Type

Complex

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser

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Gene expression (Transcription) (Homo sapiens)

- RNA Polymerase II Transcription (Homo sapiens)
  - Generic Transcription Pathway (Homo sapiens)
    - Transcriptional Regulation by TP53 (Homo sapiens)
      - Regulation of TP53 Activity (Homo sapiens)
        
        Regulation of TP53 Activity through Methylation (Homo sapiens)
        
        PRMT5 methylates TP53 (Homo sapiens)
        
        p-S15,S20,Me-R333,Me2-R335,R337-TP53 Tetramer:p-S203,S221-TTC5:EP300:JMY:PRMT5 [nucleoplasm] (Homo sapiens)
        
        p-S15,S20,Me-R333,Me2-R335,R337-TP53 Tetramer [nucleoplasm] (Homo sapiens)

Literature References

PubMed ID	Title	Journal	Year
19011621	Arginine methylation regulates the p53 response Cho, EC, Edelmann, M, Jansson, M, La Thangue, NB, Durant, ST, Kessler, B, Sheahan, S	Nat. Cell Biol.	2008

Participants

components

x 4 p-S15,S20,Me-R333,Me2-R335,R337-TP53 [nucleoplasm] (Homo sapiens)

Participates

as a component of

p-S15,S20,Me-R333,Me2-R335,R337-TP53 Tetramer:p-S203,S221-TTC5:EP300:JMY:PRMT5 [nucleoplasm] (Homo sapiens)

Inferred To

p-S15,S20,Me-R333,Me2-R335,R337-TP53 Tetramer [nucleoplasm] (Bos taurus)

p-S15,S20,Me-R333,Me2-R335,R337-TP53 Tetramer [nucleoplasm] (Canis familiaris)

p-S15,S20,Me-R333,Me2-R335,R337-TP53 Tetramer [nucleoplasm] (Danio rerio)

p-S15,S20,Me-R333,Me2-R335,R337-TP53 Tetramer [nucleoplasm] (Mus musculus)

p-S15,S20,Me-R333,Me2-R335,R337-TP53 Tetramer [nucleoplasm] (Rattus norvegicus)

p-S15,S20,Me-R333,Me2-R335,R337-TP53 Tetramer [nucleoplasm] (Sus scrofa)

p-S15,S20,Me-R333,Me2-R335,R337-TP53 Tetramer [nucleoplasm] (Xenopus tropicalis)

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