AGGF(1-290)-RAF1(279-648) fusion [cytosol]

Stable Identifier
R-HSA-6802255
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
25204415 The landscape of kinase fusions in cancer

Kim, JL, Schalm, S, Stransky, N, Lengauer, C, Cerami, E

Nat Commun 2014
External Reference Information
External Reference
Gene Names
AGGF1, GPATC7, GPATCH7, VG5Q
Chain
initiator methionine:, chain:2-714
Reference Transcript
Other Identifiers
11726731_a_at
11726732_at
11726733_s_at
11746946_a_at
11751538_a_at
11754726_a_at
16986450
208042_PM_at
208042_at
218534_PM_s_at
218534_s_at
222661_PM_at
222661_at
2756116
2816569
2816570
2816571
2816572
2816573
2816574
2816575
2816579
2816580
2816581
2816582
2816583
2816584
2816585
2816586
2816588
2816590
2816591
2816592
2816593
2816594
2816598
2816599
2816600
2816601
2816602
2816603
2816604
3273066
35065_at
35066_g_at
35067_at
3658720
46261_at
55109
55912_at
8106429
A_23_P250554
A_23_P41970
A_33_P3227666
GE55703
GO:0001525
GO:0001570
GO:0001938
GO:0003676
GO:0005515
GO:0005576
GO:0005737
GO:0007155
GO:0030154
GO:0045766
GO:0048471
GO:0048856
HMNXSV003050581
Hs.284216.0.A2_3p_at
ILMN_1776153
ILMN_2064917
PH_hs_0014722
TC05000377.hg
g8922325_3p_a_at
g9558744_3p_at
Participates
Other forms of this molecule
Modified Residues
Name
Insertion of residues 279 to 648 at 291 from UniProt:P04049 RAF1
Coordinate
291
Name
O-phospho-L-serine at 621
Coordinate
621
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Disease
Name Identifier Synonyms
prostate adenocarcinoma DOID:2526 adenocarcinoma of prostate (disorder), prostate adenocarcinoma
thyroid carcinoma DOID:3963 head and neck cancer, Thyroid
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Cross References
RefSeq
OpenTargets
GeneCards
PRO
Pharos - Targets
Orphanet
Interactors (2)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q96EZ8 MCRS1  1 0.556 3
 UniProt:O43143 DHX15  1 0.556 3
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