Netrin-4 binds DCC/UNC5A

Stable Identifier
R-HSA-593685
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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DCC and UNC5A, are also receptors for Netrin-4. The LNT domain of Netrin-4 is the key domain for this specific binding. Netrin-4 might also mediate attractive action through DCC and repulsive action through UNC5A.
Literature References
PubMed ID Title Journal Year
17174565 Characterization of the receptors for axon guidance factor netrin-4 and identification of the binding domains

Qin, S, Zhang, C, Gao, Y, Zhou, R, Yu, L

Mol Cell Neurosci 2007
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