Reactome | ACSF2 [mitochondrial matrix]

ACSF2 [mitochondrial matrix]

Stable Identifier

R-HSA-5696005

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

Acyl-CoA synthetase family member 2, mitochondrial ecNumber6.2.1.-/ecNumber, ACSF2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q96CM8 ACSF2

Gene Names

ACSF2, UNQ493/PRO1009

Chain

transit peptide:1-41, chain:42-615

Reference Genes

BioGPS Gene:80221 ACSF2

COSMIC (genes):ACSF2 ACSF2

CTD Gene:80221 ACSF2

dbSNP Gene:80221 ACSF2

ENSEMBL:ENSG00000167107 ACSF2

ENSEMBL_homo_sapiens_GENE:ENSG00000167107.13 ACSF2

HGNC:26101 ACSF2

KEGG Gene (Homo sapiens):80221 ACSF2

Monarch:80221 ACSF2

NCBI Gene:80221 ACSF2

OMIM:610465 ACSF2

UCSC:Q96CM8 ACSF2

Reference Transcript

Other Identifiers

11719035_a_at

16835816

218844_PM_at

218844_at

3726407

3726408

3726411

3726421

3726423

3726425

3726427

3726429

3726431

3726432

3726434

3726435

3726436

3726448

3726449

3726452

3726453

3726455

3726457

3726459

3726461

3726462

48011_at

60079_s_at

8008321

80221

GE83105

GO:0000166

GO:0001676

GO:0003824

GO:0004467

GO:0005515

GO:0005524

GO:0005739

GO:0005759

GO:0006629

GO:0006631

GO:0006637

GO:0006790

GO:0016874

GO:0031956

GO:0043226

GO:0047760

GO:0055086

GO:0140657

GO:1901135

HMNXSV003036815

HMNXSV003053577

PH_hs_0032521

g13376740_3p_at

Inferred To

ACSF2 [mitochondrial matrix] (Bos taurus)

ACSF2 [mitochondrial matrix] (Canis familiaris)

ACSF2 [mitochondrial matrix] (Danio rerio)

ACSF2 [mitochondrial matrix] (Gallus gallus)

ACSF2 [mitochondrial matrix] (Mus musculus)

ACSF2 [mitochondrial matrix] (Rattus norvegicus)

ACSF2 [mitochondrial matrix] (Sus scrofa)

acs-1 [mitochondrial matrix] (Caenorhabditis elegans)

acsf2 [mitochondrial matrix] (Xenopus tropicalis)

Acsf2 [mitochondrial matrix] (Drosophila melanogaster)

Cross References

RefSeq

NP_001275899.1, NP_001275897.1, NP_001275900.1, NP_001275898.1, NP_001275901.1, NP_079425.3

OpenTargets

ENSG00000167107

GeneCards

Q96CM8

HPA

ENSG00000167107-ACSF2

Ensembl

ENST00000300441, ENSG00000167107, ENSP00000300441, ENST00000502667, ENSP00000421884, ENST00000427954, ENSP00000401831

PRO

Q96CM8

Pharos - Targets

Q96CM8

HMDB Protein

HMDBP11002

Interactors (20)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q15041 AR6P1			0.83	8
UniProt:Q96DZ9 CKLF5			0.742	5
UniProt:O75208 COQ9	1	COQ9 [mitochondrial inner membrane] (R-HSA-8932994)	0.666	4
UniProt:Q6RW13 AGTRAP	2	AGTRAP(1-159)-p-BRAF(288-545) fusion [cytosol] (R-HSA-6802511) AGTRAP(1-159)-BRAF(288-545) fusion [cytosol] (R-HSA-6802262)	0.666	4
UniProt:Q96DZ9-2 CMTM5			0.556	3
UniProt:Q6Q788 APOA5	4	APOA5 [endoplasmic reticulum lumen] (R-HSA-8956716) p-APOA5 [endoplasmic reticulum lumen] (R-HSA-8956979) APOA5 [extracellular region] (R-HSA-174608) APOA5 [cytosol] (R-HSA-6784664)	0.556	3
UniProt:Q6ZPD8 DGAT2L6	1	DGAT2L6 [endoplasmic reticulum membrane] (R-HSA-8848588)	0.556	3
UniProt:Q8IYJ2-2 C10ORF67			0.556	3
UniProt:Q9Y371 SHLB1			0.556	3
UniProt:Q8IUN9 CLEC10A	1	CLEC10A [plasma membrane] (R-HSA-1472863)	0.556	3
UniProt:Q96PQ1 SIGLEC12	1	SIGLEC12 [plasma membrane] (R-HSA-197729)	0.556	3
UniProt:Q3SXY8 ARL13B	8	PolyUb-Misfolded ARL13B [lysosomal lumen] (R-HSA-9660004) PolyUb-Misfolded ARL13B [cytosol] (R-HSA-9641129) Ub-Misfolded ARL13B [cytosol] (R-HSA-9641119) Misfolded ARL13B [cytosol] (R-HSA-9640110) Misfolded ARL13B [cilium] (R-HSA-9640116) ARL13B [cilium] (R-HSA-5618181) PolyUb-Misfolded ARL13B [late endosome lumen] (R-HSA-9659986) ARL13B [plasma membrane] (R-HSA-9716787)	0.556	3
UniProt:Q6NTF9-3 Q6NTF93			0.556	3
UniProt:Q8TDT2 GP152			0.556	3
UniProt:Q9HC62 SENP2	1	SENP2 [nucleoplasm] (R-HSA-2984298)	0.556	3
UniProt:P02654 APOC1	1	APOC1 [extracellular region] (R-HSA-8855541)	0.556	3
UniProt:Q5XKP0 MICOS13	1	MIC13 (QIL1) [mitochondrial inner membrane] (R-HSA-8949561)	0.556	3
UniProt:Q8IZV5 RDH10	1	RDH10 [endoplasmic reticulum membrane] (R-HSA-2454090)	0.556	3
UniProt:O43761 SNG3			0.556	3
UniProt:O43889 CREB3	7	CREB3(1-256) [nucleoplasm] (R-HSA-8874190) CREB3(1-256) [cytosol] (R-HSA-8874135) CREB3(1-291) [Golgi membrane] (R-HSA-8874181) CREB3(257-291) [Golgi membrane] (R-HSA-8874207) CREB3 [Golgi membrane] (R-HSA-8874123) CREB3(292-371) [Golgi membrane] (R-HSA-8874173) CREB3 [endoplasmic reticulum membrane] (R-HSA-8874165)	0.553	2

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