SEC24A,B:SEC23A bind SEC22B

Stable Identifier
R-HSA-5694415
Type
Reaction [binding]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
SEC24A,B:SEC23A bind SEC22B
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Of the four human SEC24 isoforms, SEC24A and B are required for packaging the v-SNARE SEC22 into COPII vesicles. Recognition of the ER packaging epitope on SEC22 also depends on SEC23A (Mancias and Goldberg, 2007).
Literature References
PubMed ID Title Journal Year
17499046 The transport signal on Sec22 for packaging into COPII-coated vesicles is a conformational epitope

Goldberg, J, Mancias, JD

Mol. Cell 2007
Participants
Input
Output
Participates
as an event of
Orthologous Events
SEC24A,B:SEC23A bind SEC22B (Bos taurus)
SEC24A,B:SEC23A bind SEC22B (Caenorhabditis elegans)
SEC24A,B:SEC23A bind SEC22B (Canis familiaris)
SEC24A,B:SEC23A bind SEC22B (Dictyostelium discoideum)
SEC24A,B:SEC23A bind SEC22B (Drosophila melanogaster)
SEC24A,B:SEC23A bind SEC22B (Gallus gallus)
SEC24A,B:SEC23A bind SEC22B (Mus musculus)
SEC24A,B:SEC23A bind SEC22B (Plasmodium falciparum)
SEC24A,B:SEC23A bind SEC22B (Rattus norvegicus)
SEC24A,B:SEC23A bind SEC22B (Saccharomyces cerevisiae)
SEC24A,B:SEC23A bind SEC22B (Schizosaccharomyces pombe)
SEC24A,B:SEC23A bind SEC22B (Sus scrofa)
SEC24A,B:SEC23A bind SEC22B (Xenopus tropicalis)
Authored
Rothfels, K  (2015-04-18)
Reviewed
Gillespie, ME  (2015-08-18)
Created
Rothfels, K  (2015-05-21)
Cite Us!