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PALM-C100-CKAP4 [plasma membrane]
Stable Identifier
R-HSA-5686280
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Cytoskeleton-associated protein 4, CKAP4_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Surfactant metabolism (Homo sapiens)
PALM-C100-CKAP4 binds SFTPAs (Homo sapiens)
PALM-C100-CKAP4 [plasma membrane] (Homo sapiens)
PALM-C100-CKAP4:SFTPAs [plasma membrane] (Homo sapiens)
PALM-C100-CKAP4 [plasma membrane] (Homo sapiens)
PALM-C100-CKAP4 transports SFTPAs from extracellular region to lamellar body (Homo sapiens)
PALM-C100-CKAP4:SFTPAs [plasma membrane] (Homo sapiens)
PALM-C100-CKAP4 [plasma membrane] (Homo sapiens)
ZDHHC2 transfers PALM from PALM-CoA to CKAP4 (Homo sapiens)
PALM-C100-CKAP4 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q07065 CKAP4
Gene Names
CKAP4
Chain
chain:1-602
Reference Genes
BioGPS Gene:10970 CKAP4
COSMIC (genes):CKAP4 CKAP4
CTD Gene:10970 CKAP4
dbSNP Gene:10970 CKAP4
ENSEMBL:ENSG00000136026 CKAP4
HGNC:16991 CKAP4
KEGG Gene (Homo sapiens):10970 CKAP4
Monarch:10970 CKAP4
NCBI Gene:10970 CKAP4
OMIM:618595 CKAP4
UCSC:Q07065 CKAP4
Reference Transcript
RefSeq:NM_006825.3 CKAP4
Other Identifiers
0002030576
10970
11726583_s_at
11746889_a_at
1225
16769585
200998_s_at
200999_s_at
278
32529_at
3469686
3469688
3469689
3469690
3469691
3469692
3469693
3469694
3469704
3469705
3469706
3469707
3469708
3469709
3469710
3469711
792
7966035
A0A024RBH2
A_23_P48056
AAH82972
AAH94824
AC079174
AK223563
BAD97283
BC082972
BC094824
CAA49535
CCDS9103
CH471054
CKAP4
CKAP4-201
EAW97772
EAW97773
ENSG00000136026
ENSP00000367265
ENST00000378026
ENST00000378026.4
EntrezGene:10970
EntrezGene:CKAP4
F8VVU0
g5803112_3p_a_at
GE59965
GO:0002376
GO:0003674
GO:0003723
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005737
GO:0005764
GO:0005773
GO:0005783
GO:0005788
GO:0005789
GO:0005791
GO:0005811
GO:0005829
GO:0005856
GO:0005886
GO:0006464
GO:0006810
GO:0008150
GO:0016020
GO:0016021
GO:0016192
GO:0016607
GO:0031410
GO:0032991
GO:0035577
GO:0035579
GO:0036464
GO:0042599
GO:0043226
GO:0043312
GO:0043687
GO:0044267
GO:0048471
GO:0070062
HGNC:16991
HPA000278
HPA000792
HPA001225
Hs.74368.0.A1_3p_a_at
IPR028428
NM_006825
NP_006816
PH_hs_0004243
TC12001917.hg
TC12003061.hg
TC12003062.hg
UPI00000723B9
X69910
X69910_at
Participant Of
output
ZDHHC2 transfers PALM from PALM-CoA to CKAP4
hasComponent
PALM-C100-CKAP4:SFTPAs [plasma membrane]
input
PALM-C100-CKAP4 binds SFTPAs
Other forms of this molecule
PALM-C100-CKAP4 [lamellar body]
CKAP4 [azurophil granule membrane]
CKAP4 [plasma membrane]
CKAP4 [specific granule membrane]
p-CKAP4 [endoplasmic reticulum lumen]
CKAP4 [endoplasmic reticulum lumen]
Inferred To
PALM-C100-CKAP4 [plasma membrane] (Bos taurus)
PALM-C100-CKAP4 [plasma membrane] (Canis familiaris)
PALM-C100-CKAP4 [plasma membrane] (Danio rerio)
PALM-C100-CKAP4 [plasma membrane] (Gallus gallus)
PALM-C100-CKAP4 [plasma membrane] (Mus musculus)
PALM-C100-CKAP4 [plasma membrane] (Rattus norvegicus)
PALM-C100-CKAP4 [plasma membrane] (Sus scrofa)
PALM-C100-CKAP4 [plasma membrane] (Xenopus tropicalis)
Modified Residues
Name
S-palmitoyl-L-cysteine (palmitoyl group) at 100
Coordinate
100
Modification
palmitoyl group
PsiMod Name
S-palmitoyl-L-cysteine [MOD:00115]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-palmitoyl-L-cysteine.
Cross References
RefSeq
NP_006816.2
OpenTargets
ENSG00000136026
GeneCards
Q07065
PRO
Q07065
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P04578-PRO_0000038428 ENV
0.462
2
UniProt:O43493 TGOLN2
8
TGOLN2 [plasma membrane]
(R-HSA-8864458)
TGOLN2 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869127)
TGOLN2 [Golgi membrane]
(R-HSA-434342)
TGOLN2 [cytoplasmic vesicle membrane]
(R-HSA-429818)
TGOLN2 [trans-Golgi network membrane]
(R-HSA-6811008)
TGOLN2 [transport vesicle]
(R-HSA-6811011)
p-TGOLN2 [endoplasmic reticulum lumen]
(R-HSA-8956886)
TGOLN2 [endoplasmic reticulum lumen]
(R-HSA-8956702)
0.462
2
UniProt:P04578 env
7
Transmembrane protein gp41 (P04578) [cytosol]
(R-HIV-189359)
Surface protein gp120 (P04578) [cytosol]
(R-HIV-189269)
Glycosylated Envelope glycoprotein gp160 [Golgi membrane]
(R-HIV-3149443)
Envelope glycoprotein gp160 [endoplasmic reticulum membrane]
(R-HIV-189343)
Transmembrane protein gp41 [viral envelope]
(R-HIV-171195)
Surface protein gp120 [viral envelope]
(R-HIV-171211)
ENV [viral envelope]
(R-HIV-173439)
0.462
4
UniProt:P27824 CANX
2
CANX [integral component of lumenal side of endoplasmic reticulum membrane]
(R-HSA-983091)
CANX [endoplasmic reticulum lumen]
(R-HSA-195906)
0.462
2
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