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BRAP [cytosol]
Stable Identifier
R-HSA-5672938
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser for interactor UniProt:Q7Z569 BRAP
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
FLT3 Signaling (Homo sapiens)
RAF/MAP kinase cascade (Homo sapiens)
Negative regulation of MAPK pathway (Homo sapiens)
BRAP binds KSR1:MARK3 (Homo sapiens)
BRAP [cytosol] (Homo sapiens)
BRAP binds RAS:GTP (Homo sapiens)
BRAP [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
MAPK family signaling cascades (Homo sapiens)
MAPK1/MAPK3 signaling (Homo sapiens)
RAF/MAP kinase cascade (Homo sapiens)
Negative regulation of MAPK pathway (Homo sapiens)
BRAP binds KSR1:MARK3 (Homo sapiens)
BRAP [cytosol] (Homo sapiens)
BRAP binds RAS:GTP (Homo sapiens)
BRAP [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q7Z569 BRAP
Gene Names
BRAP, RNF52
Chain
chain:1-592
Reference Genes
BioGPS Gene:8315 BRAP
COSMIC (genes):BRAP BRAP
CTD Gene:8315 BRAP
dbSNP Gene:8315 BRAP
ENSEMBL:ENSG00000089234 BRAP
HGNC:1099 BRAP
KEGG Gene (Homo sapiens):8315 BRAP
Monarch:8315 BRAP
NCBI Gene:8315 BRAP
OMIM:604986 BRAP
UCSC:Q7Z569 BRAP
Reference Transcript
RefSeq:NM_006768.4 BRAP
Other Identifiers
0001740195
11724633_at
11751151_a_at
16770256
209922_at
209923_s_at
213473_at
3471701
3471703
3471705
3471706
3471707
3471708
3471709
3471710
3471711
3471712
3471713
3471724
3471726
3471727
3471728
3471729
3471730
3471733
3471734
35500_at
40357
41512_at
58820
63075_s_at
7966427
8315
A_23_P53614
AAB88538
AAC24200
AAI36699
AAI36700
AAP93638
AC002996
AC137055
AF035620
AF035950
AK299326
AY332222
BAG61333
BC136698
BC136699
BRAP
BRAP-202
CCDS9154
CH471054
EAW97972
ENSG00000089234
ENSP00000403524
ENST00000419234
ENST00000419234.8
EntrezGene:8315
EntrezGene:BRAP
g3252871_3p_a_at
GE54285
GO:0000151
GO:0000165
GO:0003674
GO:0003676
GO:0004842
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005635
GO:0005737
GO:0005829
GO:0006464
GO:0007165
GO:0007265
GO:0008139
GO:0008150
GO:0008270
GO:0009968
GO:0016567
GO:0016740
GO:0031965
GO:0032991
GO:0042802
GO:0043167
GO:0043226
GO:0046872
GO:0061630
HGNC:1099
HPA040357
HPA058820
Hs.122764.1.S1_3p_s_at
IPR001607
IPR001841
IPR011422
IPR013083
IPR034932
IPR035979
J3KNN7
MIM:604986
NM_006768
NP_006759
PF02148
PF07576
PF13639
PH_hs_0025720
SM00184
SM00290
TC12001974.hg
UPI00001AF597
XM_005253944
XM_017019992
XP_005254001
XP_016875481
Participant Of
input
BRAP binds KSR1:MARK3
BRAP binds RAS:GTP
hasComponent
BRAP:KSR1:MARK3 [cytosol]
p21 RAS:GTP:BRAP [plasma membrane]
Other forms of this molecule
ub-BRAP [cytosol]
Inferred To
BRAP [cytosol] (Bos taurus)
BRAP [cytosol] (Caenorhabditis elegans)
BRAP [cytosol] (Canis familiaris)
BRAP [cytosol] (Danio rerio)
BRAP [cytosol] (Dictyostelium discoideum)
BRAP [cytosol] (Gallus gallus)
BRAP [cytosol] (Mus musculus)
BRAP [cytosol] (Plasmodium falciparum)
BRAP [cytosol] (Rattus norvegicus)
BRAP [cytosol] (Saccharomyces cerevisiae)
BRAP [cytosol] (Schizosaccharomyces pombe)
BRAP [cytosol] (Sus scrofa)
BRAP [cytosol] (Xenopus tropicalis)
Cross References
RefSeq
NP_006759.3
OpenTargets
ENSG00000089234
GeneCards
Q7Z569
PRO
Q7Z569
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q7Z569 BRAP
2
BRAP [cytosol]
(R-HSA-5672938)
ub-BRAP [cytosol]
(R-HSA-5674001)
0.573
2
UniProt:Q5JVL4 EFHC1
0.547
2
UniProt:P01112 HRAS
17
HRAS Q61L [plasma membrane]
(R-HSA-6802452)
HRAS Q61R [plasma membrane]
(R-HSA-6802458)
HRAS Q61K [plasma membrane]
(R-HSA-6802442)
HRAS G13R [plasma membrane]
(R-HSA-6802368)
HRAS G12V [plasma membrane]
(R-HSA-6802350)
HRAS G12S [plasma membrane]
(R-HSA-6802343)
HRAS T58I [plasma membrane]
(R-HSA-9656014)
HRAS G13C [plasma membrane]
(R-HSA-9656008)
HRAS K117R [plasma membrane]
(R-HSA-9656010)
HRAS G13V [plasma membrane]
(R-HSA-9656579)
HRAS G13D [plasma membrane]
(R-HSA-9656572)
HRAS G13S [plasma membrane]
(R-HSA-9656574)
HRAS K117N [plasma membrane]
(R-HSA-9656603)
HRAS G12D [plasma membrane]
(R-HSA-9656564)
HRAS G12C [plasma membrane]
(R-HSA-9656561)
HRAS [plasma membrane]
(R-HSA-62717)
S-Farn-Me-2xPalmS HRAS [plasma membrane]
(R-HSA-9647912)
0.524
3
UniProt:O75969 AKAP3
0.508
2
UniProt:P38398 BRCA1
5
SUMO1-K109-BRCA1 [nucleoplasm]
(R-HSA-2997644)
SUMO2,3-BRCA1 [nucleoplasm]
(R-HSA-2997624)
p-S988,S1387,S1423,S1524,S1547-BRCA1 [nucleoplasm]
(R-HSA-5683800)
BRCA1 [nucleoplasm]
(R-HSA-50949)
p-S1387,S1423,S1524,S1547-BRCA1 [nucleoplasm]
(R-HSA-75234)
0.508
3
UniProt:Q9BW85 YJU2
0.488
2
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