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RUNX1 [plasma membrane]
Stable Identifier
R-HSA-5667138
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Runt-related transcription factor 1, RUNX1_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)
Organic cation/anion/zwitterion transport (Homo sapiens)
Organic cation transport (Homo sapiens)
SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol (Homo sapiens)
RUNX1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q01196 RUNX1
Gene Names
RUNX1, AML1, CBFA2
Chain
chain:1-453
Reference Genes
BioGPS Gene:861 RUNX1
COSMIC (genes):RUNX1 RUNX1
CTD Gene:861 RUNX1
dbSNP Gene:861 RUNX1
ENSEMBL:ENSG00000159216 RUNX1
HGNC:10471 RUNX1
KEGG Gene (Homo sapiens):861 RUNX1
Monarch:861 RUNX1
NCBI Gene:861 RUNX1
OMIM:151385 RUNX1
UCSC:Q01196 RUNX1
Reference Transcript
RefSeq:NM_001001890.2 RUNX1
RefSeq:XM_005261068.3 RUNX1
RefSeq:XM_011529766.2 RUNX1
RefSeq:NM_001122607.1 RUNX1
RefSeq:NM_001754.4 RUNX1
Other Identifiers
0001500338
11728761_a_at
11728762_x_at
11732933_a_at
11742191_a_at
11745150_x_at
11753289_s_at
11762910_x_at
1CMO
1CO1
1E50
1H9D
1LJM
2026_at
208129_x_at
209359_x_at
209360_s_at
210365_at
210805_3p_x_at
210805_x_at
211180_x_at
211181_x_at
211182_x_at
211620_3p_x_at
211620_x_at
37912
3930361
3930362
3930363
3930364
3930365
3930366
3930367
3930373
3930392
3930393
3930404
3930405
3930411
3930427
3930428
3930433
3930434
3930435
3930436
3930437
3930438
3930439
3930440
3930441
3930442
3930443
3930444
3930446
3930506
3930507
3930508
3930509
3930510
3930529
393_s_at
39421_at
4176
8070194
861
943_at
A0A0C4DG58
A8MZI9
A_24_P34155
A_24_P96403
A_33_P3211804
A_33_P3211809
A_33_P3211818
AAA03086
AAA51720
AAB29907
AAB33729
AAB33730
AAB33731
AAB34819
AAB34820
AAB51691
AAC05246
AAC05247
AAI36381
AAI36382
AAI44054
AF015262
AF025841
AJ229043
AP000330
AP000331
AP000332
AP000333
AP000334
BAA01426
BAA03089
BAA03559
BAA03560
BAA07902
BAA07903
BAA07904
BAA14020
BAA14021
BAA14022
BC136380
BC136381
BC144053
C9JWM1
CAA13070
CAA56092
CAA62464
CAA62466
CCDS13639
CCDS42922
CCDS46646
CH471079
D10570
D13979
D14822
D14823
D43967
D43968
D43968_at
D43969
D89788
D89789
D89790
EAX09769
EAX09770
ENSG00000159216
ENSP00000300305
ENSP00000340690
ENSP00000351123
ENSP00000409227
ENST00000300305
ENST00000300305.7
ENST00000344691
ENST00000344691.8
ENST00000358356
ENST00000358356.9
ENST00000437180
ENST00000437180.5
EntrezGene:861
EntrezGene:RUNX1
g1752816_3p_a_at
g1932819_3p_a_at
g1932819_3p_x_at
g966994_3p_at
g966996_3p_a_at
GE57221
GO:0000122
GO:0000228
GO:0000790
GO:0000977
GO:0000978
GO:0000981
GO:0001228
GO:0001959
GO:0002062
GO:0002376
GO:0003674
GO:0003677
GO:0003700
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005829
GO:0006355
GO:0007155
GO:0007165
GO:0007267
GO:0008150
GO:0008283
GO:0009058
GO:0010629
GO:0016513
GO:0022607
GO:0030097
GO:0030111
GO:0030154
GO:0030182
GO:0030854
GO:0032743
GO:0032991
GO:0033146
GO:0034330
GO:0034641
GO:0043167
GO:0043226
GO:0043231
GO:0043371
GO:0043378
GO:0044212
GO:0045589
GO:0045616
GO:0045637
GO:0045652
GO:0045766
GO:0045893
GO:0045944
GO:0048646
GO:0048856
GO:0048935
GO:0050855
GO:0071425
GO:1902036
GO:2000810
H9KVB1
HGNC:10471
HPA004176
HPA037912
ILMN_1654941
ILMN_1669335
ILMN_1730797
ILMN_1801504
IPR000040
IPR008967
IPR012346
IPR013524
IPR013711
IPR016554
IPR027384
L21756
L34598
LRG_482
LRG_482t1
MIM:151385
MIM:601399
MIM:601626
NM_001001890
NM_001122607
NM_001754
NP_001001890
NP_001116079
NP_001745
PF00853
PF08504
PH_hs_0041180
PR00967
RUNX1
RUNX1-201
RUNX1-202
RUNX1-203
RUNX1-207
S50186
S60998
S69002
S74092
S76345
S76346
S76350
S78158
S78159
S78496
U19601
UPI000002B2EA
UPI0000141569
UPI000015FE6A
V9GYT3
V9GYT5
X79549
X90976
X90976_s_at
X90979
XM_005261068
XM_005261069
XM_011529766
XM_011529767
XM_011529770
XM_017028487
XP_005261125
XP_005261126
XP_011528068
XP_011528069
XP_011528072
XP_016883976
XR_937576
This entity regulates
Negatively
SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol
Other forms of this molecule
RUNX1 [nucleoplasm]
MeR206,MeR210-RUNX1 [nucleoplasm]
p-7Y-RUNX1 [nucleoplasm]
p-S249,S273,T276-RUNX1 [nucleoplasm]
Inferred To
Homologues of RUNX1 [plasma membrane] (Danio rerio)
Homologues of RUNX1 [plasma membrane] (Drosophila melanogaster)
RUNX1 [plasma membrane] (Bos taurus)
RUNX1 [plasma membrane] (Caenorhabditis elegans)
RUNX1 [plasma membrane] (Canis familiaris)
RUNX1 [plasma membrane] (Danio rerio)
RUNX1 [plasma membrane] (Drosophila melanogaster)
RUNX1 [plasma membrane] (Gallus gallus)
RUNX1 [plasma membrane] (Mus musculus)
RUNX1 [plasma membrane] (Sus scrofa)
RUNX1 [plasma membrane] (Xenopus tropicalis)
Cross References
RefSeq
NP_001745.2
,
XP_005261125.1
,
NP_001116079.1
,
NP_001001890.1
,
XP_011528068.1
OpenTargets
ENSG00000159216
GeneCards
Q01196
PRO
Q01196
Orphanet
15235
PDB
1LJM
,
1E50
,
1CMO
,
1H9D
,
1CO1
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13951 CBFB
1
CBFB [nucleoplasm]
(R-HSA-8865293)
0.713
3
UniProt:Q00534 CDK6
3
CDK6 [nucleoplasm]
(R-HSA-141283)
CDK6 [cytosol]
(R-HSA-68336)
p-T177-CDK6 [nucleoplasm]
(R-HSA-69628)
0.656
5
UniProt:Q9H2X6 HIPK2
3
p-HIPK2 [nucleoplasm]
(R-HSA-6799375)
SUMO1-K32-HIPK2 [nucleoplasm]
(R-HSA-4090405)
HIPK2 [nucleoplasm]
(R-HSA-3215222)
0.639
4
UniProt:P17542 TAL1
1
TAL1 [nucleoplasm]
(R-HSA-8956511)
0.623
3
UniProt:Q15723 ELF2
1
ELF2 [nucleoplasm]
(R-HSA-8938898)
0.544
2
UniProt:Q9GZV5 WWTR1
3
WWTR1 [nucleoplasm]
(R-HSA-1629775)
WWTR1 [cytosol]
(R-HSA-1629773)
p-S89-WWTR1 [cytosol]
(R-HSA-2028665)
0.527
2
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