CSNK1A1 and ADRBK1 dissociate from p-SMO dimer

Stable Identifier
R-HSA-5633040
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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After phosphorylating the SMO dimer, CSNK1A1 and ADRBK1 presumably dissociate, although this has not been demonstrated explicitly (Chen et al, 2011).
Literature References
PubMed ID Title Journal Year
21695114 Sonic Hedgehog dependent phosphorylation by CK1? and GRK2 is required for ciliary accumulation and activation of smoothened

Yue, T, Jia, J, Ma, G, Sasai, N, Briscoe, J, Jiang, J, Chen, Y

PLoS Biol. 2011
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