Demethylase KDM1A binds KLK2 and KLK3 promoters

Stable Identifier
R-HSA-5625849
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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PKN1-mediated phosphorylation of histone H3 threonine residue 12 (also labeled in literature as Thr11) enables recruitment of KDM1A (LSD1) demethylase to AR-regulated promoters KLK2 and KLK3 (PSA) (Metzger et al. 2008).
Literature References
PubMed ID Title Journal Year
18066052 Phosphorylation of histone H3 at threonine 11 establishes a novel chromatin mark for transcriptional regulation

Kunowska, N, Patnaik, D, Schüle, R, Metzger, E, Wissmann, M, Potier, N, Scheidtmann, KH, Higgins, JM, Friedrichs, N, Buettner, R, Fischer, K, Yin, N

Nat. Cell Biol. 2008
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