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p-T718-PKN3 [cytosol]
Stable Identifier
R-HSA-5623654
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
p-T718-PRK3
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase Effectors (Homo sapiens)
RHO GTPases activate PKNs (Homo sapiens)
PDPK1 phosphorylates PKN1,2,3 (Homo sapiens)
p-T774-PKN1,p-T816-PKN2,p-T718-PKN3 [cytosol] (Homo sapiens)
p-T718-PKN3 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6P5Z2 PKN3
Gene Names
PKN3, PKNBETA
Chain
chain:1-889
Reference Genes
BioGPS Gene:29941 PKN3
COSMIC (genes):PKN3 PKN3
CTD Gene:29941 PKN3
dbSNP Gene:29941 PKN3
ENSEMBL:ENSG00000160447 PKN3
HGNC:17999 PKN3
KEGG Gene (Homo sapiens):29941 PKN3
Monarch:29941 PKN3
NCBI Gene:29941 PKN3
OMIM:610714 PKN3
UCSC:Q6P5Z2 PKN3
Reference Transcript
RefSeq:NM_013355.4 PKN3
Other Identifiers
0006110270
04070+2.7.11.13
11722938_a_at
11722939_a_at
17089819
226299_at
29941
3190684
3190685
3190686
3190688
3190689
3190690
3190691
3190692
3190693
3190694
3190696
3190697
3190698
3190699
3190700
3190701
3190702
3190705
3190707
3190708
3190709
3190710
3190711
3190713
3190714
3190715
3190717
3190718
3190719
45390
55643_at
58305
64669_at
8158380
85649_at
A0A024R8D6
A_23_P258982
A_33_P3220202
AAH62558
AB019692
AL441992
BAA85625
BC062558
CCDS6908
CH471090
EAW87824
EAW87825
ENSG00000160447
ENSP00000291906
ENST00000291906
ENST00000291906.4
EntrezGene:29941
EntrezGene:PKN3
GE53516
GO:0000166
GO:0003674
GO:0004672
GO:0004674
GO:0004697
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005737
GO:0005794
GO:0006464
GO:0006468
GO:0007165
GO:0008150
GO:0010631
GO:0016301
GO:0016310
GO:0016740
GO:0017049
GO:0018105
GO:0019899
GO:0035556
GO:0040011
GO:0043167
GO:0043226
GO:0048471
GO:0048870
HGNC:17999
HPA045390
HPA058305
Hs.44101.0.S1_3p_at
ILMN_1797184
IPR000719
IPR000961
IPR008271
IPR011009
IPR011072
IPR017441
IPR017892
IPR036274
IPR037313
MIM:610714
NM_001317926
NM_013355
NP_001304855
NP_037487
PF00069
PF00433
PF02185
PH_hs_0028145
PKN3
PKN3-201
SM00133
SM00220
SM00742
TC09000699.hg
UPI000013E087
XM_005251946
XM_006717080
XM_017014649
XM_017014650
XP_005252003
XP_006717143
XP_016870138
XP_016870139
Participant Of
hasCandidate
p-T774-PKN1,p-T816-PKN2,p-T718-PKN3 [cytosol]
Other forms of this molecule
PKN3 [cytosol]
Inferred To
Homologues of p-T718-PKN3 [cytosol] (Danio rerio)
Homologues of p-T718-PKN3 [cytosol] (Dictyostelium discoideum)
Homologues of p-T718-PKN3 [cytosol] (Schizosaccharomyces pombe)
phospho-p-T718-PKN3 [cytosol] (Bos taurus)
phospho-p-T718-PKN3 [cytosol] (Caenorhabditis elegans)
phospho-p-T718-PKN3 [cytosol] (Canis familiaris)
phospho-p-T718-PKN3 [cytosol] (Danio rerio)
phospho-p-T718-PKN3 [cytosol] (Dictyostelium discoideum)
phospho-p-T718-PKN3 [cytosol] (Drosophila melanogaster)
phospho-p-T718-PKN3 [cytosol] (Gallus gallus)
phospho-p-T718-PKN3 [cytosol] (Mus musculus)
phospho-p-T718-PKN3 [cytosol] (Saccharomyces cerevisiae)
phospho-p-T718-PKN3 [cytosol] (Schizosaccharomyces pombe)
phospho-p-T718-PKN3 [cytosol] (Sus scrofa)
phospho-p-T718-PKN3 [cytosol] (Xenopus tropicalis)
Modified Residues
Name
O-phospho-L-threonine at 718
Coordinate
718
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
NP_037487.2
OpenTargets
ENSG00000160447
GeneCards
Q6P5Z2
PRO
Q6P5Z2
HMDB Protein
HMDBP09509
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:A1A4S6 ARHGAP10
1
ARHGAP10 [cytosol]
(R-HSA-195125)
0.581
4
UniProt:Q22038
14
RHOD [cytosol]
(R-CEL-194848)
RHOF [cytosol]
(R-CEL-194888)
RHOD [plasma membrane]
(R-CEL-194889)
RHOF [plasma membrane]
(R-CEL-194921)
RHOA [secretory granule membrane]
(R-CEL-6804980)
RHOF [secretory granule membrane]
(R-CEL-6804978)
RHOA [ficolin-1-rich granule membrane]
(R-CEL-6804971)
RHOA [endoplasmic reticulum membrane]
(R-CEL-5672082)
RHOB [cytosol]
(R-CEL-194855)
RHOD [endosome membrane]
(R-CEL-5666090)
RHOB [endosome membrane]
(R-CEL-5666064)
RHOA [cytosol]
(R-CEL-194866)
RHOB [plasma membrane]
(R-CEL-194891)
RHOA [plasma membrane]
(R-CEL-194510)
0.544
2
UniProt:Q08379 GOLGA2
3
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.488
2
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