HOXA4 gene is transcribed

Stable Identifier
R-HSA-5617877
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
cytosol, nucleoplasm
ReviewStatus
5/5
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HOXA4 gene is transcribed
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The HOXA4 gene is transcribed to yield mRNA (Doerksen et al. 1996). In mouse cells, microRNAs miR-196a-2, miR-196b, and miRNA miR-222 target Hoxa4 mRNA untranslated regions. In mouse embryos Hoxa4 mRNA is observed in rhombomere 7, mesoderm (including somites, lung, and kidney), rostral-dorsal stomach, rostral prececal gut, and large intestine.
Literature References
PubMed ID Title Journal Year
8759021 Functional interaction between a RARE and an AP-2 binding site in the regulation of the human HOX A4 gene promoter

Kannan, P, Doerksen, LF, Pratt, D, Tainsky, MA, Bhattacharya, A

Nucleic Acids Res. 1996
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
atRA:RARA,B:RXRA at active HOXA4 chromatin [nucleoplasm] (Homo sapiens)
Active Unit
NCOA3 [nucleoplasm]
CTCF [nucleoplasm]
EP300 [nucleoplasm]
RXRA:RARA,B:atRA [nucleoplasm]
RNA Polymerase II holoenzyme complex (generic) [nucleoplasm]
Inferred From
Hoxa4 gene is transcribed (Mus musculus)
Authored
Rezsohazy, R  (2015-11-15)
May, B  (2014-08-08)
Reviewed
Blasi, F  (2015-05-13)
Created
May, B  (2014-08-15)
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