Expression of CRYPTOCHROME-2

Stable Identifier
R-HSA-549470
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm, cytosol
ReviewStatus
5/5
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Expression of CRYPTOCHROME-2
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The CRYPTOCHROME-2 (CRY2) gene is transcribed to yield mRNA and the mRNA is translated to yield CRY2 protein (Kobayashi et al. 1998, Thompson et al. 2003, also inferred from mouse homologs). As inferred from mouse, the CRY2 protein shows circadian rhythm in the suprachiasmatic nucleus (SCN) and in peripheral tissues. The mRNA shows circadian rhythm in muscle but not in the SCN. Expression is dependent on CLOCK.
Literature References
PubMed ID Title Journal Year
9801304 Characterization of photolyase/blue-light receptor homologs in mouse and human cells

Kanno, S, Smit, B, Yasui, A, Kobayashi, K, Takao, M, van der Horst, GT

Nucleic Acids Res 1998
14507900 Expression of the blue-light receptor cryptochrome in the human retina

Ebright, JN, Kelly, U, Bowes Rickman, C, Rickman, DW, Sancar, A, Thompson, CL, Shaw, SJ

Invest Ophthalmol Vis Sci 2003
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Output
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as an event of
Inferred From
Expression of Cryptochrome-2 (Cry2) (Mus musculus)
Authored
May, B  (2010-03-11)
Reviewed
Delaunay, F  (2010-06-23)
Hirota, T  (2010-06-23)
Kay, SA  (2010-06-23)
Albrecht, U  (2010-06-23)
D'Eustachio, P  (2009-05-27)
Created
May, B  (2010-03-21)
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