Formation of MSH1:PMS2 Complex

Stable Identifier
R-HSA-5444523
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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The heterodimer of MLH1 and PMS2 and is required for mismatch repair. The complex is known as MutL with mutations causing deficiencies in DNA mismatch repair.

Literature References
PubMed ID Title Journal Year
8128251 Mutation of a mutL homolog in hereditary colon cancer

Papadopoulos, N, Nicolaides, NC, Wei, YF, Ruben, SM, Carter, KC, Rosen, CA, Haseltine, WA, Fleischmann, RD, Fraser, CM, Adams, MD

Science 1994
Participants
Participant Of
Orthologous Events
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Created