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p-CHP1 [plasma membrane]
Stable Identifier
R-HSA-5333747
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
phosphorylated Calcineurin B homologous protein 1, CHP1_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of carbohydrates (Homo sapiens)
Glycosaminoglycan metabolism (Homo sapiens)
Hyaluronan metabolism (Homo sapiens)
Hyaluronan uptake and degradation (Homo sapiens)
HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ (Homo sapiens)
HA:HAR:HYAL2:SLC9A1:pCHP:Ca2+ [plasma membrane] (Homo sapiens)
SLC9A1:p-CHP:Ca2+ [plasma membrane] (Homo sapiens)
p-CHP1:Ca2+ [plasma membrane] (Homo sapiens)
p-CHP1 [plasma membrane] (Homo sapiens)
SLC9A1:p-CHP:Ca2+ [plasma membrane] (Homo sapiens)
p-CHP1:Ca2+ [plasma membrane] (Homo sapiens)
p-CHP1 [plasma membrane] (Homo sapiens)
Hyaluronidase 2 (HYAL2) hydrolyses HA into 20kDa fragments (Homo sapiens)
HA:HAR:HYAL2:SLC9A1:pCHP:Ca2+ [plasma membrane] (Homo sapiens)
SLC9A1:p-CHP:Ca2+ [plasma membrane] (Homo sapiens)
p-CHP1:Ca2+ [plasma membrane] (Homo sapiens)
p-CHP1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q99653 CHP1
Gene Names
CHP1, CHP
Chain
initiator methionine:, chain:2-195
Reference Genes
BioGPS Gene:11261 CHP1
COSMIC (genes):CHP1 CHP1
CTD Gene:11261 CHP1
dbSNP Gene:11261 CHP1
ENSEMBL:ENSG00000187446 CHP1
ENSEMBL_homo_sapiens_GENE:ENSG00000187446.12 CHP1
HGNC:17433 CHP1
KEGG Gene (Homo sapiens):11261 CHP1
Monarch:11261 CHP1
NCBI Gene:11261 CHP1
OMIM:606988 CHP1
UCSC:Q99653 CHP1
Reference Transcript
RefSeq:NM_007236.4 CHP1
Other Identifiers
11261
11754517_a_at
11756650_a_at
207993_PM_s_at
207993_s_at
214665_PM_s_at
214665_s_at
2862214
2934425
35018_at
3590343
3590347
3590349
3590352
3590353
3590359
3590360
3590361
3590362
3590363
3590364
3590366
3590367
3907071
49347_at
7982878
80180_at
A_14_P116755
A_23_P100111
A_23_P112801
GE55456
GE59284
GO:0000139
GO:0001578
GO:0001933
GO:0004860
GO:0005215
GO:0005509
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005737
GO:0005783
GO:0005793
GO:0005794
GO:0005856
GO:0005886
GO:0005925
GO:0006351
GO:0006355
GO:0006469
GO:0006486
GO:0006611
GO:0006629
GO:0006813
GO:0006886
GO:0006913
GO:0007010
GO:0007264
GO:0008017
GO:0008092
GO:0010923
GO:0012505
GO:0015031
GO:0015385
GO:0015459
GO:0015630
GO:0016020
GO:0019900
GO:0022406
GO:0023052
GO:0030133
GO:0031122
GO:0031397
GO:0031410
GO:0031953
GO:0032088
GO:0032417
GO:0035725
GO:0036211
GO:0042308
GO:0043226
GO:0045121
GO:0046872
GO:0048306
GO:0050821
GO:0051222
GO:0051453
GO:0055085
GO:0060050
GO:0061024
GO:0061025
GO:0070062
GO:0070885
GO:0071073
GO:0071468
GO:0090314
GO:0098772
GO:1901135
GO:1990351
HMNXSV003016165
HMNXSV003035406
Hs.85301.3.S1_3p_s_at
ILMN_1779401
TC15000304.hg
U61538_at
g6005730_3p_a_at
Participates
as a component of
p-CHP1:Ca2+ [plasma membrane] (Homo sapiens)
Inferred To
phospho-chpf-1 [plasma membrane]
(Caenorhabditis elegans)
phospho-chp1 [plasma membrane]
(Xenopus tropicalis)
phospho-CHP1 [plasma membrane]
(Canis familiaris)
phospho-p-CHP1 [plasma membrane]
(Bos taurus)
phospho-p-CHP1 [plasma membrane]
(Gallus gallus)
phospho-p-CHP1 [plasma membrane]
(Mus musculus)
phospho-p-CHP1 [plasma membrane]
(Rattus norvegicus)
phospho-p-CHP1 [plasma membrane]
(Sus scrofa)
Modified Residues
Name
phosphorylated residue at unknown position
PsiMod Name
phosphorylated residue [MOD:00696]
PsiMod Definition
A protein modification that effectively replaces a hydrogen atom with a phosphate group.
Cross References
RefSeq
NP_009167.1
OpenTargets
ENSG00000187446
GeneCards
Q99653
HPA
ENSG00000187446-CHP1
Ensembl
ENSP00000335632
,
ENSG00000187446
,
ENST00000334660
PRO
Q99653
Pharos - Targets
Q99653
HMDB Protein
HMDBP02240
PDB
7X2U
,
2E30
,
7DSV
,
7DSX
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
calcium(2+) [ChEBI:29108]
20
Ca2+ [platelet dense granule lumen]
(R-ALL-114582)
Ca2+ [endosome membrane]
(R-ALL-5210949)
Ca2+ [sarcoplasmic reticulum lumen]
(R-ALL-2855229)
Ca2+ [mitochondrial intermembrane space]
(R-ALL-8949232)
Ca2+ [endocytic vesicle lumen]
(R-ALL-8851519)
Ca2+ [lysosomal lumen]
(R-ALL-1606834)
Ca2+ [endoplasmic reticulum-Golgi intermediate compartment]
(R-ALL-9706979)
Ca2+ [Golgi lumen]
(R-ALL-167012)
Ca2+ [platelet dense tubular network lumen]
(R-ALL-139827)
Ca2+ [platelet dense tubular network membrane]
(R-ALL-141090)
Ca2+ [plasma membrane]
(R-ALL-140648)
Ca2+ [secretory granule lumen]
(R-ALL-216801)
Ca2+ [nuclear envelope]
(R-ALL-2318767)
Ca2+ [nucleoplasm]
(R-ALL-29496)
Ca2+ [mitochondrial matrix]
(R-ALL-8949220)
Ca2+ [mitochondrial inner membrane]
(R-ALL-1524102)
Ca2+ [endoplasmic reticulum membrane]
(R-ALL-1500625)
Ca2+ [endoplasmic reticulum lumen]
(R-ALL-111875)
Ca2+ [cytosol]
(R-ALL-74016)
Ca2+ [extracellular region]
(R-ALL-74112)
0.558
2
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.483
4
UniProt:P05919 vpu
6
VPU (P05919) protein [cytosol]
(R-HIV-173223)
VPU (P05919) [endoplasmic reticulum membrane]
(R-HIV-180550)
VPU (P05919) protein [extracellular region]
(R-HIV-175522)
VPU (P05919) protein [nucleoplasm]
(R-HIV-175200)
VPU (P05919) [Golgi membrane]
(R-HIV-3149439)
VPU (P05919) [plasma membrane]
(R-HIV-3149423)
0.462
2
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