In the absence of stress HSF1 is predominantly monomeric and is thought to be repressed in its inactive monomeric state by the following mechanisms:
Garrido, C, Gilquin, B, Zhang, Y, Khochbin, S, Vourc'h, C, Matthias, P, Yao, TP, Fritah, S, Kwon, SH, Caron, C, Boyault, C
misfolded protein binding activity of HSF1:HSP90:HDAC6:VCP:PTGES3 [cytosol]
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