CYP2D6 [endoplasmic reticulum membrane]

Stable Identifier
R-HSA-52679
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
Cytochrome P450 2D6 , CYPIID6, P450-DB1, Debrisoquine 4-hydroxylase
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P10635 CYP2D6
Gene Names
CYP2D6, CYP2DL1
Chain
chain:1-497
Reference Genes
BioGPS Gene:1565 CYP2D6
COSMIC (genes):CYP2D6 CYP2D6
CTD Gene:1565 CYP2D6
dbSNP Gene:1565 CYP2D6
ENSEMBL:ENSG00000100197 CYP2D6
ENSEMBL_homo_sapiens_GENE:ENSG00000100197.23 CYP2D6
ENSEMBL_homo_sapiens_GENE:ENSG00000275211.4 CYP2D6
HGNC:2625 CYP2D6
KEGG Gene (Homo sapiens):1565 CYP2D6
Monarch:1565 CYP2D6
NCBI Gene:1565 CYP2D6
OMIM:124030 CYP2D6
UCSC:P10635 CYP2D6
Reference Transcript
Other Identifiers
11733907_s_at
11733908_x_at
1565
16935560
207498_3p_s_at
207498_PM_s_at
207498_s_at
38507_at
3962295
3962298
3962299
3962303
3962306
3962308
3962309
3962312
3962318
3962321
3962326
8076424
8180391
A_23_P143734
GO:0003824
GO:0004497
GO:0005506
GO:0005737
GO:0005739
GO:0005783
GO:0005789
GO:0006629
GO:0006631
GO:0006805
GO:0008202
GO:0008203
GO:0008210
GO:0009804
GO:0009820
GO:0009822
GO:0016020
GO:0016098
GO:0016491
GO:0016705
GO:0016712
GO:0019369
GO:0020037
GO:0033076
GO:0042178
GO:0042572
GO:0042759
GO:0043226
GO:0043231
GO:0046483
GO:0046872
GO:0051100
GO:0062187
GO:0062188
GO:0062189
GO:0070989
GO:0090350
HMNXSV003002247
HMNXSV003005926
ILMN_1740648
ILMN_2383124
TC22001361.hg
TC22001430.hg
X07618_s_at
g4503222_3p_s_at
Participates
as a member of
as a candidate of
Inferred To
cyp-33d1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp-33d3 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
Cyp2d22 [endoplasmic reticulum membrane] (Mus musculus)
CYP2D15 [endoplasmic reticulum membrane] (Canis familiaris)
zgc:195056 [endoplasmic reticulum membrane] (Danio rerio)
cyp-35a2 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp-35a1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
Homologues of CYP2D6 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
Homologues of CYP2D6 [endoplasmic reticulum membrane] (Danio rerio)
Homologues of CYP2D6 [endoplasmic reticulum membrane] (Dictyostelium discoideum)
Homologues of CYP2D6 [endoplasmic reticulum membrane] (Drosophila melanogaster)
cyp-35a5 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp-35a3 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp-35a4 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
zgc:153647 [endoplasmic reticulum membrane] (Danio rerio)
cyp-33c1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
zgc:110749 [endoplasmic reticulum membrane] (Danio rerio)
cyp-33c5 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp-33c12 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp-33c3 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp-33c7 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp-33c9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp-33e2 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp-34a1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp2j29 [endoplasmic reticulum membrane] (Danio rerio)
cyp2j27 [endoplasmic reticulum membrane] (Danio rerio)
cyp-33b1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp2j25 [endoplasmic reticulum membrane] (Danio rerio)
cyp2j23 [endoplasmic reticulum membrane] (Danio rerio)
cyp-34a9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp-35b2 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp-34a5 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp-34a7 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
zgc:153597 [endoplasmic reticulum membrane] (Danio rerio)
cyp2x10.1 [endoplasmic reticulum membrane] (Danio rerio)
cyp2j21 [endoplasmic reticulum membrane] (Danio rerio)
dach-1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp2j30 [endoplasmic reticulum membrane] (Danio rerio)
cyp-34a10 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
zgc:171945 [endoplasmic reticulum membrane] (Danio rerio)
cyp2aa3v1 [endoplasmic reticulum membrane] (Danio rerio)
zgc:162502 [endoplasmic reticulum membrane] (Danio rerio)
cyp-33a1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
daf-9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp2v2 [endoplasmic reticulum membrane] (Danio rerio)
LOC100495359 [endoplasmic reticulum membrane] (Xenopus tropicalis)
zgc:91876 [endoplasmic reticulum membrane] (Danio rerio)
cyp-35c1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp-33c2 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
CYP2D6 [endoplasmic reticulum membrane] (Bos taurus)
CYP2D6 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
CYP2D6 [endoplasmic reticulum membrane] (Danio rerio)
CYP2D6 [endoplasmic reticulum membrane] (Dictyostelium discoideum)
CYP2D6 [endoplasmic reticulum membrane] (Drosophila melanogaster)
CYP2D6 [endoplasmic reticulum membrane] (Gallus gallus)
CYP2D6 [endoplasmic reticulum membrane] (Rattus norvegicus)
CYP2D6 [endoplasmic reticulum membrane] (Sus scrofa)
cyp-33c6 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp-33c11 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp-33c4 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp-33c8 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp-33e1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp-33e3 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp-34a2 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp2x12 [endoplasmic reticulum membrane] (Danio rerio)
cyp2j28 [endoplasmic reticulum membrane] (Danio rerio)
cyp-35b1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp-34a8 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp-35b3 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp2j24 [endoplasmic reticulum membrane] (Danio rerio)
cyp-34a6 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp-23a1 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
cyp2j22 [endoplasmic reticulum membrane] (Danio rerio)
Cross References
RefSeq
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC target
ZINC - Biogenic
PRO
PDB
ZINC - Investigational
ZINC - Metabolites
HPA
GeneCards
Ensembl
Pharos - Targets
ZINC - Predictions - Purchasable
Orphanet
HMDB Protein
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