botG:SYT1:GT1b [plasma membrane]

Stable Identifier
R-HSA-5250975
Type
Complex
Species
Homo sapiens
Related Species
Clostridium botulinum
Compartment
plasma membrane
Synonyms
BoNT/G:SYT1:GT1b
GO Cellular Component
host cell plasma membrane (0020002)
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
23647335 Botulinum neurotoxin G binds synaptotagmin-II in a mode similar to that of serotype B: tyrosine 1186 and lysine 1191 cause its lower affinity

Mahrhold, S, Strotmeier, J, Rummel, A, Eichner, T, Binz, T, Willjes, G

Biochemistry 2013
22454523 Botulinum neurotoxin D-C uses synaptotagmin I and II as receptors, and human synaptotagmin II is not an effective receptor for type B, D-C and G toxins

Pitkin, RM, Tepp, WH, Berntsson, RP, Stenmark, P, Dong, M, Peng, L, Johnson, EA

J. Cell. Sci. 2012
Participants
components
Participates
as an output of
as an input of
Disease
Name Identifier Synonyms
botulism DOID:11976 Botulism (disorder), Intoxication with Clostridium botulinum toxin, Botulism, Infection due to clostridium botulinum, Botulism, Foodborne botulism, botulism, Botulism, Botulism, Botulism, Food poisoning due to Clostridium botulinum, Botulism poisoning
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