Reactome | SMARCD2 [nucleoplasm]

SMARCD2 [nucleoplasm]

Stable Identifier

R-HSA-5225626

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2, SMRD2_HUMAN

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Homo sapiens)

- RNA Polymerase II Transcription (Homo sapiens)
  - Generic Transcription Pathway (Homo sapiens)
    - Transcriptional regulation by RUNX1 (Homo sapiens)
      - RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known (Homo sapiens)
        
        RUNX1 binds the SWI/SNF complex (Homo sapiens)
        
        RUNX1:CBFB:SWI/SNF [nucleoplasm] (Homo sapiens)
        
        SWI/SNF chromatin remodelling complex [nucleoplasm] (Homo sapiens)
        
        SWI/SNF additional components [nucleoplasm] (Homo sapiens)
        
        SMARCD2 [nucleoplasm] (Homo sapiens)
        
        SWI/SNF chromatin remodelling complex [nucleoplasm] (Homo sapiens)
        
        SWI/SNF additional components [nucleoplasm] (Homo sapiens)
        
        SMARCD2 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q92925 SMARCD2

Gene Names

SMARCD2, BAF60B, PRO2451

Chain

chain:1-531

Reference Genes

BioGPS Gene:6603 SMARCD2

COSMIC (genes):SMARCD2 SMARCD2

CTD Gene:6603 SMARCD2

dbSNP Gene:6603 SMARCD2

ENSEMBL:ENSG00000108604 SMARCD2

ENSEMBL_homo_sapiens_GENE:ENSG00000108604.18 SMARCD2

HGNC:11107 SMARCD2

KEGG Gene (Homo sapiens):6603 SMARCD2

Monarch:6603 SMARCD2

NCBI Gene:6603 SMARCD2

OMIM:601736 SMARCD2

UCSC:Q92925 SMARCD2

Reference Transcript

Other Identifiers

11717063_s_at

11742080_a_at

11747710_a_at

16847644

201827_PM_at

201827_at

34694_at

34695_at

3766416

3766417

3766418

3766419

3766420

3766422

3766423

3766425

3766426

3766428

3766429

3766431

3766432

3766433

3766437

3766438

3766439

3766440

455_at

6603

8017460

GE87462

GO:0000278

GO:0000776

GO:0000785

GO:0002376

GO:0003677

GO:0003712

GO:0003713

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0006281

GO:0006325

GO:0006337

GO:0006338

GO:0006351

GO:0006355

GO:0006357

GO:0007059

GO:0007155

GO:0016363

GO:0016514

GO:0016586

GO:0030071

GO:0030154

GO:0031492

GO:0032991

GO:0035060

GO:0043226

GO:0045582

GO:0045597

GO:0045663

GO:0045893

GO:0048856

GO:0070316

GO:0140092

GO:0140110

GO:2000045

GO:2000781

GO:2000819

HMNXSV003012771

ILMN_1692684

PH_hs_0013265

TC17001787.hg

U66618_at

g6642761_3p_at

Participates

as a member of

SMARCD1,2,3 [nucleoplasm] (Homo sapiens)

as a candidate of

SWI/SNF additional components [nucleoplasm] (Homo sapiens)

Inferred To

SNF12 [nucleoplasm] (Saccharomyces cerevisiae)

snf12-1 [nucleoplasm] (Dictyostelium discoideum)

swsn-2.2 [nucleoplasm] (Caenorhabditis elegans)

Smarcd2 [nucleoplasm] (Mus musculus)

Smarcd2 [nucleoplasm] (Rattus norvegicus)

smarcd2 [nucleoplasm] (Xenopus tropicalis)

ham-3 [nucleoplasm] (Caenorhabditis elegans)

ssr3 [nucleoplasm] (Schizosaccharomyces pombe)

Bap60 [nucleoplasm] (Drosophila melanogaster)

Homologues of SMARCD2 [nucleoplasm] (Caenorhabditis elegans)

Homologues of SMARCD2 [nucleoplasm] (Saccharomyces cerevisiae)

RSC6 [nucleoplasm] (Saccharomyces cerevisiae)

SMARCD2 [nucleoplasm] (Bos taurus)

SMARCD2 [nucleoplasm] (Canis familiaris)

SMARCD2 [nucleoplasm] (Gallus gallus)

SMARCD2 [nucleoplasm] (Sus scrofa)

Cross References

RefSeq

NP_001317369.1, NP_001091896.1

OpenTargets

ENSG00000108604

HPA

ENSG00000108604-SMARCD2

GeneCards

Q92925

Ensembl

ENSP00000392617, ENSP00000318451, ENST00000448276, ENST00000323347, ENSG00000108604

PRO

Q92925

Pharos - Targets

Q92925

Orphanet

26299