PXN binds p-6Y,S732-PTK2

Stable Identifier
R-HSA-5218838
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
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PXN binds p-6Y,S732-PTK2
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Paxillin (PXN) is a multidomain scaffolding protein localized primarily in focal adhesions. It binds with focal adhesion kinase (FAK1, also known as PTK2) and is recruited to the focal adhesions. VEGF induced a quick and marked increase in the recruitment of both paxillin and vinculin to FAK (Abedi & Zachary 1997).
Literature References
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Output
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as an event of
Orthologous Events
PXN binds p-6Y,S732-PTK2 (Bos taurus)
PXN binds p-6Y,S732-PTK2 (Canis familiaris)
PXN binds p-6Y,S732-PTK2 (Gallus gallus)
PXN binds p-6Y,S732-PTK2 (Mus musculus)
PXN binds p-6Y,S732-PTK2 (Rattus norvegicus)
PXN binds p-6Y,S732-PTK2 (Sus scrofa)
Authored
Garapati, P V  (2013-08-30)
Reviewed
Ballmer-Hofer, K  (2014-05-12)
Welsh, M  (2014-05-12)
Berger, P  (2014-05-12)
Created
Garapati, P V  (2013-12-19)
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