PIAS2,3,4 SUMOylate RORA with SUMO1

Stable Identifier
R-HSA-4719436
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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PIAS2-2 (PIASx-alpha), PIAS3, and PIAS4 SUMOylate RORA with SUMO1 at lysine-240 (Hwang et al. 2009). SUMOylation increases transcriptional activation by RORA.

Literature References
PubMed ID Title Journal Year
19041634 SUMOylation of RORalpha potentiates transcriptional activation function

Hwang, EJ, Lee, JM, Jeong, J, Park, JH, Yang, Y, Lim, JS, Kim, JH, Baek, SH, Kim, KI

Biochem. Biophys. Res. Commun. 2009
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
SUMO transferase activity of PIAS2-2,PIAS3,PIAS4 [nucleoplasm]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created