PIAS2,3,4 SUMOylate RORA with SUMO2

Stable Identifier
R-HSA-4719413
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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PIAS2-2 (PIASx-alpha, PIAS3, and PIAS4 SUMOylate RORA with SUMO2 at lysine-240 (Hwang et al. 2009). SUMOylation increases the transcriptional activity of RORA.

Literature References
PubMed ID Title Journal Year
19041634 SUMOylation of RORalpha potentiates transcriptional activation function

Hwang, EJ, Lee, JM, Jeong, J, Park, JH, Yang, Y, Lim, JS, Kim, JH, Baek, SH, Kim, KI

Biochem. Biophys. Res. Commun. 2009
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
SUMO transferase activity of PIAS2-2,PIAS3,PIAS4 [nucleoplasm]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created