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PELI2 [cytosol]
Stable Identifier
R-HSA-450694
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Pellino-2, Protein pellino homolog 2, PELI2_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-1 family signaling (Homo sapiens)
Interleukin-1 signaling (Homo sapiens)
hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. (Homo sapiens)
hp-IRAK1:Pellino, IRAK4:Pellino [cytosol] (Homo sapiens)
IRAK4: Pellino-1,2,3 [cytosol] (Homo sapiens)
Pellino 1,2,3 [cytosol] (Homo sapiens)
PELI2 [cytosol] (Homo sapiens)
hp-IRAK1: Pellino-1,2,3 [cytosol] (Homo sapiens)
Pellino 1,2,3 [cytosol] (Homo sapiens)
PELI2 [cytosol] (Homo sapiens)
hp-IRAK1,hp-IRAK4 bind Pellino1,2,3 (Homo sapiens)
Pellino 1,2,3 [cytosol] (Homo sapiens)
PELI2 [cytosol] (Homo sapiens)
hp-IRAK1:Pellino, IRAK4:Pellino [cytosol] (Homo sapiens)
IRAK4: Pellino-1,2,3 [cytosol] (Homo sapiens)
Pellino 1,2,3 [cytosol] (Homo sapiens)
PELI2 [cytosol] (Homo sapiens)
hp-IRAK1: Pellino-1,2,3 [cytosol] (Homo sapiens)
Pellino 1,2,3 [cytosol] (Homo sapiens)
PELI2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9HAT8 PELI2
Gene Names
PELI2
Chain
chain:1-420
Reference Genes
BioGPS Gene:57161 PELI2
COSMIC (genes):PELI2 PELI2
CTD Gene:57161 PELI2
dbSNP Gene:57161 PELI2
ENSEMBL:ENSG00000139946 PELI2
ENSEMBL_homo_sapiens_GENE:ENSG00000139946.11 PELI2
HGNC:8828 PELI2
KEGG Gene (Homo sapiens):57161 PELI2
Monarch:57161 PELI2
NCBI Gene:57161 PELI2
OMIM:614798 PELI2
UCSC:Q9HAT8 PELI2
Reference Transcript
RefSeq:NM_021255.2 PELI2
Other Identifiers
11724068_at
11724069_at
16784498
219132_PM_at
219132_at
3537165
3537166
3537167
3537181
3537201
3537204
3537206
3537209
3537210
3537211
3537212
57161
62136_at
7974533
A_14_P139723
A_23_P65532
GE56634
GO:0000209
GO:0001934
GO:0003824
GO:0005515
GO:0005829
GO:0008592
GO:0016567
GO:0016740
GO:0023052
GO:0034450
GO:0036211
GO:0043123
GO:0043410
GO:0061630
GO:0140096
HMNXSV003020289
HMNXSV003038369
ILMN_1780132
PH_hs_0003194
TC14000332.hg
g10864062_3p_at
Participates
as a member of
Pellino 1,2,3 [cytosol] (Homo sapiens)
Other forms of this molecule
p-PELI2 [cytosol]
Inferred To
peli-1 [cytosol]
(Caenorhabditis elegans)
PELI2 [cytosol]
(Bos taurus)
PELI2 [cytosol]
(Canis familiaris)
PELI2 [cytosol]
(Sus scrofa)
Peli2 [cytosol]
(Mus musculus)
Peli2 [cytosol]
(Rattus norvegicus)
Pli [cytosol]
(Drosophila melanogaster)
Cross References
RefSeq
NP_067078.1
OpenTargets
ENSG00000139946
HPA
ENSG00000139946-PELI2
GeneCards
Q9HAT8
Ensembl
ENSP00000267460
,
ENST00000267460
,
ENSG00000139946
PRO
Q9HAT8
Pharos - Targets
Q9HAT8
PDB
3EGA
,
3EGB
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P51617 IRAK1
14
p-S376,T387-IRAK1 [cytosol]
(R-HSA-446687)
K63polyUb-hp-IRAK1 [endosome membrane]
(R-HSA-975112)
p-S,T-IRAK1 [cytosol]
(R-HSA-3149574)
K63polyUb-hp-IRAK1 [cytosol]
(R-HSA-451565)
p-T209-IRAK1 [endosome membrane]
(R-HSA-975189)
p-T209,T387-IRAK1 [endosome membrane]
(R-HSA-975117)
IRAK1 [endosome membrane]
(R-HSA-975127)
p-2S,S376,T,T209,T387-IRAK1 [endosome membrane]
(R-HSA-975157)
IRAK1 [plasma membrane]
(R-HSA-937045)
p-T209-IRAK1 [plasma membrane]
(R-HSA-937031)
p-T209,T387-IRAK1 [plasma membrane]
(R-HSA-166279)
p-2S,S376,T,T209,T387-IRAK1 [plasma membrane]
(R-HSA-937011)
p-2S,S376,T,T209,T387-IRAK1 [cytosol]
(R-HSA-446682)
IRAK1 [cytosol]
(R-HSA-446639)
0.743
4
UniProt:Q9NWZ3 IRAK4
9
IRAK4 R12C [cytosol]
(R-HSA-5602511)
IRAK4 Q293TER [cytosol]
(R-HSA-5602426)
IRAK4 E402TER [cytosol]
(R-HSA-5602517)
p-T342,T345,S346-IRAK4 [cytosol]
(R-HSA-446649)
IRAK4 [endosome membrane]
(R-HSA-975167)
p-T342,T345,S346-IRAK4 [endosome membrane]
(R-HSA-975149)
IRAK4 [plasma membrane]
(R-HSA-937051)
p-T342,T345,S346-IRAK4 [plasma membrane]
(R-HSA-936957)
IRAK4 [cytosol]
(R-HSA-166081)
0.593
3
UniProt:Q12891 HYAL2
1
HYAL2 [plasma membrane]
(R-HSA-2160919)
0.556
3
UniProt:P35227 PCGF2
1
PCGF2 [nucleoplasm]
(R-HSA-389115)
0.556
3
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