Reactome | Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA

Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA

Stable Identifier

R-HSA-450517

Type

Reaction [binding]

Species

Homo sapiens

Compartment

cytosol

ReviewStatus

5/5

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Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA

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Butyrate response factor 1 (BRF1) binds AU-rich elements in the 3' untranslated region of mRNAs.

Literature References

PubMed ID	Title	Journal	Year
17030608	BRF1 protein turnover and mRNA decay activity are regulated by protein kinase B at the same phosphorylation sites Gross, B, Benjamin, D, Min, L, Moroni, C, Schmidlin, M	Mol Cell Biol	2006
15538381	The ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase B Stoecklin, G, Lu, M, Hess, D, Gross, B, Mallaun, M, Leuenberger, SA, Gherzi, R, Moroni, C, Hemmings, BA, Schmidlin, M	EMBO J	2004
18326031	The AU-rich element mRNA decay-promoting activity of BRF1 is regulated by mitogen-activated protein kinase-activated protein kinase 2 Chou, CF, Luber, CA, Maitra, S, Chen, CY, Mann, M, Lee, KY	RNA	2008
12198173	Functional cloning of BRF1, a regulator of ARE-dependent mRNA turnover Lu, M, Stoecklin, G, Gross, B, Leuenberger, S, Mallaun, M, Kitamura, T, Raineri, I, Colombi, M, Moroni, C, Schmidlin, M	EMBO J	2002