CHL1 interacts with NRP1

Stable Identifier
R-HSA-445083
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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CHL1 binds the Sema3A receptor, Neuropilin-1 (NP-1), via a conserved sequence in the Ig1 domain, and acts as obligate coreceptor to mediate Sema3A-induced growth cone collapse and axon repulsion.
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