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Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane]
Stable Identifier
R-HSA-444999
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
L1CAM interactions (Homo sapiens)
Recycling pathway of L1 (Homo sapiens)
Formation of clathrin coated vesicle (Homo sapiens)
L1:AP-2 Clathrin complex [clathrin-coated endocytic vesicle] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
L1:clathrin-coated vesicle [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
Interaction of NUMB with L1 (Homo sapiens)
CRMP-2:NUMB:alpha adaptin [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
L1:NUMB:CRMP-2:alpha-adaptin [clathrin-coated endocytic vesicle] (Homo sapiens)
CRMP-2:NUMB:alpha adaptin [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
L1 binds to AP-2 Clathrin complex (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
L1:clathrin-coated vesicle [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
Phosphorylation of L1 by ERK (Homo sapiens)
L1:AP-2 Clathrin complex [endosome] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
pL1 (S1204, 1248):ERK2:clathrin-dynamin complex [endosome] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
Phosphorylation of L1 by p90rsk (Homo sapiens)
L1:AP-2 Clathrin complex [endosome] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
pL1 (S1152):p90rsk:clathrin-dynamin complex [endosome] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
Reinsertion of L1 into the plasma membrane (Homo sapiens)
AP2 clathrin:L1:KIF4:microtubule [cytosol] (Homo sapiens)
L1:AP-2 Clathrin complex [endosome] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
Transport of L1 from C-domain to P-domain (Homo sapiens)
AP2 clathrin:L1:KIF4:microtubule [cytosol] (Homo sapiens)
L1:AP-2 Clathrin complex [endosome] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
L1:AP-2 Clathrin complex [endosome] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
Transport of L1 into endosomes (Homo sapiens)
L1:AP-2 Clathrin complex [clathrin-coated endocytic vesicle] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
L1:AP-2 Clathrin complex [endosome] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
MHC class II antigen presentation (Homo sapiens)
Internalization of MHC II:Ii clathrin coated vesicle (Homo sapiens)
Clathrin coated MHC class II alpha/beta/Ii nonamer [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
Recruitment of clathrin coated vesicle by Ii (Homo sapiens)
Clathrin coated MHC class II alpha/beta/Ii nonamer [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by NTRKs (Homo sapiens)
Signaling by NTRK1 (TRKA) (Homo sapiens)
Retrograde neurotrophin signalling (Homo sapiens)
Axonal transport of NGF:Trk complexes (Homo sapiens)
Activated TrkA receptor complex:Clathrin-coated vesicle:Endophilin [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
Activated TrkA receptor complex:Clathrin-coated vesicle:dynein:dynactin complex [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
Endocytosis (internalization) of clathrin-coated vesicle (Homo sapiens)
Activated TrkA receptor complex:Clathrin-coated vesicle [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
Activated TrkA receptor complex:Clathrin-coated vesicle:Endophilin [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
Formation of clathrin-coated vesicle (Homo sapiens)
Activated TrkA receptor complex:Clathrin-coated vesicle [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
Plasma lipoprotein assembly, remodeling, and clearance (Homo sapiens)
Plasma lipoprotein clearance (Homo sapiens)
LDL clearance (Homo sapiens)
PCSK9:LDLR bind to Clathrin (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
PCSK9:LDLR:Clathrin:AP2 [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
PCSK9:LDLR:Clathrin-coated vesicle transport from plasma membrane to endolysosome (Homo sapiens)
PCSK9:LDLR:Clathrin:AP2 [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
VLDLR internalisation and degradation (Homo sapiens)
VLDLR:PCSK9 binds Clathrin-coated vesicles (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
VLDL:PCSK9:Clathrin:AP2 [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
VLDLR:PCSK9:Clathrin-coated vesicle translocates from the plasma membrane to lysosomal membrane (Homo sapiens)
VLDL:PCSK9:Clathrin:AP2 [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Clathrin-mediated endocytosis (Homo sapiens)
BAR domain proteins recruit dynamin (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
Cargo recognition for clathrin-mediated endocytosis (Homo sapiens)
Epsin family proteins bind ubiquitinated cargo (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
Clathrin recruits PIK3C2A (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
Endophilins recruit synaptojanins to the clathrin-coated pit (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
F- and N- BAR domain proteins bind the clathrin-coated pit (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
SNX9 recruits components of the actin polymerizing machinery (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [plasma membrane] (Homo sapiens)
ubiquitinated cargo [plasma membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Homo sapiens)
Clathrin:AP-2 complex [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane] (Homo sapiens)
Participants
members
AP2A1 [plasma membrane]
(Homo sapiens)
AP2A2(1-939) [plasma membrane]
(Homo sapiens)
Participates
as a component of
CRMP-2:NUMB:alpha adaptin [plasma membrane] (Homo sapiens)
AP-2 complex [plasma membrane] (Homo sapiens)
Inferred To
APL3 [plasma membrane]
(Saccharomyces cerevisiae)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane]
(Bos taurus)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane]
(Caenorhabditis elegans)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane]
(Canis familiaris)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane]
(Mus musculus)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane]
(Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane]
(Sus scrofa)
apl3 [plasma membrane]
(Schizosaccharomyces pombe)
AP-2alpha [plasma membrane]
(Drosophila melanogaster)
ap2a1-2 [plasma membrane]
(Dictyostelium discoideum)
AP2A2(1-939) [plasma membrane]
(Gallus gallus)
Ghost homologue of Adaptor protein complex 2 (AP-2) large adaptins [plasma membrane]
(Danio rerio)
AP2A1 [plasma membrane]
(Xenopus tropicalis)
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