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TAS1R2:TAS1R3 [plasma membrane]
Stable Identifier
R-HSA-444621
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Sweet taste receptor
Locations in the PathwayBrowser
Expand all
Sensory Perception (Homo sapiens)
Sensory perception of taste (Homo sapiens)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Homo sapiens)
GNAT3 exchanges GDP for GTP in TAS1R2:TAS1R3:sweet compound:GNAT3:GDP:GNB1,3:GNG13 (Homo sapiens)
TAS1R2:TAS1R3:Sweet compound:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3 [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet compound:GNAT3:GTP:GNB1,3:GNG13 [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3 [plasma membrane] (Homo sapiens)
Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) (Homo sapiens)
TAS1R2:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3 [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet compound:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3 [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:sweet compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding TAS1R2:TAS1R3:sweet compound, GNAT3:GTP, and GNB1,3:GNG13 (Homo sapiens)
TAS1R2:TAS1R3:Sweet compound:GNAT3:GTP:GNB1,3:GNG13 [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3 [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3 [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3 [plasma membrane] (Homo sapiens)
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3 [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3 [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class C/3 (Metabotropic glutamate/pheromone receptors) (Homo sapiens)
T1R2/T1R3 dimer is a sweet taste receptor (Homo sapiens)
TAS1R2:TAS1R3 [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3 [plasma membrane] (Homo sapiens)
Participants
components
TAS1R2 [plasma membrane]
(Homo sapiens)
TAS1R3 [plasma membrane]
(Homo sapiens)
Participates
as a component of
TAS1R2:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Homo sapiens)
TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Homo sapiens)
as an input of
T1R2/T1R3 dimer is a sweet taste receptor (Homo sapiens)
Inferred To
TAS1R2:TAS1R3 [plasma membrane]
(Bos taurus)
TAS1R2:TAS1R3 [plasma membrane]
(Canis familiaris)
TAS1R2:TAS1R3 [plasma membrane]
(Danio rerio)
TAS1R2:TAS1R3 [plasma membrane]
(Mus musculus)
TAS1R2:TAS1R3 [plasma membrane]
(Rattus norvegicus)
TAS1R2:TAS1R3 [plasma membrane]
(Sus scrofa)
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