Phosphorylation of FADK1

Stable Identifier
R-HSA-418872
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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FADK1 interacts with the C-terminal P3 domain of DCC complexed with Netrin-1, and undergoes tyrosine phosphorylation and activation. Netrin-1-DCC binding thus leads to the autophosphorylation of tyrosine 393 in FADK1.

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein tyrosine kinase activity of NTN1:DCC oligomer:PTK2 [plasma membrane]
Physical Entity
Activity
Inferred From
Authored
Reviewed
Created