Reactome | NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane]

NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane]

Stable Identifier

R-HSA-418839

Type

Complex

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Netrin-1:pDCC dimer:pFADK1

Locations in the PathwayBrowser

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Developmental Biology (Homo sapiens)

- Nervous system development (Homo sapiens)
  - Axon guidance (Homo sapiens)
    - Netrin-1 signaling (Homo sapiens)
      - DCC mediated attractive signaling (Homo sapiens)
        
        Activation of Cdc42 (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Homo sapiens)
        
        Activation of Rac1 (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:RAC1:GTP [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Homo sapiens)
        
        DCC interacting NCK-1 (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Homo sapiens)
        
        Phosphorylation of DCC by Fyn (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Homo sapiens)
        
        Recruitment and activation of N-WASP by Cdc42 (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP:WASL:PIP2 [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Homo sapiens)
        
        Recruitment of ABLIM to the plasma membrane (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:RAC1:GTP [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:RAC1:GTP:ABLIM [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:RAC1:GTP [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Homo sapiens)
        
        RhoGTPase GEF's recruited to DCC (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1 [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Homo sapiens)

Participants

components

Participates

as a component of

NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] (Homo sapiens)

Inferred To

NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Bos taurus)

NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Caenorhabditis elegans)

NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Canis familiaris)

NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Danio rerio)

NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Drosophila melanogaster)

NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Gallus gallus)

NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Mus musculus)

NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Rattus norvegicus)

NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] (Xenopus tropicalis)

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