FOXM1 binds CCNB1 promoter

Stable Identifier
R-HSA-4088307
Type
Reaction
Species
Homo sapiens
Compartment
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Summation

The MuvB complex (consisting of LIN9, LIN37, LIN52, LIN54 and RBBP4), together with MYBL2 (B-MYB), recruits FOXM1 to CHR motifs in the promoter of the CCNB1 (cyclin B1) gene (Sadasivam et al. 2012, Chen et al. 2013).

Literature References
PubMed ID Title Journal Year
23109430 The forkhead transcription factor FOXM1 controls cell cycle-dependent gene expression through an atypical chromatin binding mechanism

Chen, X, Müller, GA, Quaas, M, Fischer, M, Han, N, Stutchbury, B, Sharrocks, AD, Engeland, K

Mol. Cell. Biol. 2013
22391450 The MuvB complex sequentially recruits B-Myb and FoxM1 to promote mitotic gene expression

Sadasivam, S, Duan, S, DeCaprio, JA

Genes Dev. 2012
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