PIAS1,3 SUMOylate NRIP1 with SUMO1

Stable Identifier
R-HSA-4086036
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
PIAS1,3 SUMOylate NRIP1 with SUMO1
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

PIAS1,3 SUMOylate NRIP1 (RIP140) at lysine 756 and lysine-1154 with SUMO1 (Rytinki et al. 2008). SUMOylation enhances transcription repression by NRIP1.

Literature References
PubMed ID Title Journal Year
18211901 SUMOylation modulates the transcription repressor function of RIP140

Rytinki, MM, Palvimo, JJ

J. Biol. Chem. 2008
Participants
Input
Output
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
SUMO transferase activity of PIAS1,3 [nucleoplasm]
Physical Entity
PIAS1,3 [nucleoplasm]
Activity
SUMO transferase activity (0019789)
Orthologous Events
PIAS1,3 SUMOylate NRIP1 with SUMO1 (Bos taurus)
PIAS1,3 SUMOylate NRIP1 with SUMO1 (Canis familiaris)
PIAS1,3 SUMOylate NRIP1 with SUMO1 (Danio rerio)
PIAS1,3 SUMOylate NRIP1 with SUMO1 (Gallus gallus)
PIAS1,3 SUMOylate NRIP1 with SUMO1 (Mus musculus)
PIAS1,3 SUMOylate NRIP1 with SUMO1 (Rattus norvegicus)
PIAS1,3 SUMOylate NRIP1 with SUMO1 (Sus scrofa)
PIAS1,3 SUMOylate NRIP1 with SUMO1 (Xenopus tropicalis)
Authored
May, B  (2013-08-05)
Reviewed
Niskanen, E  (2018-05-09)
Niskanen, E  (2018-08-08)
Created
May, B  (2013-08-06)