SUMOylation of UBE2I with SUMO1

Stable Identifier
R-HSA-4085350
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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UBE2I (UBC9) is SUMOylated at lysine-14 with SUMO1 (Knipscheer et al. 2008). SUMOylation alters the target specificity of UBE2I, decreasing its SUMOylation activity towards RanGAP1 and increasing it towards SP100.

Literature References
PubMed ID Title Journal Year
18691969 Ubc9 sumoylation regulates SUMO target discrimination

Knipscheer, P, Flotho, A, Klug, H, Olsen, JV, van Dijk, WJ, Fish, A, Johnson, ES, Mann, M, Sixma, TK, Pichler, A

Mol. Cell 2008
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
SUMO transferase activity of SUMO1:C93-UBE2I [nucleoplasm]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created