SUMOylation of NCOA1 with SUMO1

Stable Identifier
R-HSA-4085296
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
SUMOylation of SRC1 with SUMO1
Locations in the PathwayBrowser
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NCOA1 (SRC1) is SUMOylated at lysine-732 and lysine-774 with SUMO1 (Chauchereau et al. 2003). SUMOylation enhances interaction between NCOA1 and the progesterone receptor and causes NCOA1 to be retained in the nucleus.

Literature References
PubMed ID Title Journal Year
12529333 Sumoylation of the progesterone receptor and of the steroid receptor coactivator SRC-1

Chauchereau, A, Amazit, L, Quesne, M, Guiochon-Mantel, A, Milgrom, E

J. Biol. Chem. 2003
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
SUMO transferase activity of SUMO1:C93-UBE2I [nucleoplasm]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created