Reactome | ISL1 [nucleoplasm]

ISL1 [nucleoplasm]

Stable Identifier

R-HSA-400478

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Insulin gene enhancer protein ISL-1, ISL1_HUMAN, Islet-1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P61371 ISL1

Gene Names

ISL1

Chain

chain:1-349

Reference Genes

BioGPS Gene:3670 ISL1

COSMIC (genes):ISL1 ISL1

CTD Gene:3670 ISL1

dbSNP Gene:3670 ISL1

ENSEMBL:ENSG00000016082 ISL1

ENSEMBL_homo_sapiens_GENE:ENSG00000016082.15 ISL1

HGNC:6132 ISL1

KEGG Gene (Homo sapiens):3670 ISL1

Monarch:3670 ISL1

NCBI Gene:3670 ISL1

OMIM:600366 ISL1

UCSC:P61371 ISL1

Reference Transcript

RefSeq:NM_002202.2 ISL1

Other Identifiers

11725757_at

11725758_at

16984612

206104_PM_at

206104_at

2808943

2808944

2808945

2808947

2808950

2808954

2808957

2808960

2808961

2808962

2808963

3670

39990_at

8105220

A_14_P112433

A_14_P201897

A_23_P81529

GE58893

GO:0000122

GO:0000785

GO:0000976

GO:0000978

GO:0000981

GO:0000987

GO:0001228

GO:0001755

GO:0003007

GO:0003013

GO:0003139

GO:0003148

GO:0003151

GO:0003203

GO:0003215

GO:0003266

GO:0003677

GO:0003682

GO:0005515

GO:0005634

GO:0005694

GO:0005737

GO:0006351

GO:0006355

GO:0006366

GO:0006954

GO:0007409

GO:0007507

GO:0008283

GO:0008284

GO:0010468

GO:0010575

GO:0012501

GO:0016922

GO:0021520

GO:0021522

GO:0021524

GO:0021559

GO:0021983

GO:0023052

GO:0030154

GO:0030182

GO:0030331

GO:0031016

GO:0031290

GO:0031333

GO:0032024

GO:0032725

GO:0032729

GO:0032730

GO:0032731

GO:0032735

GO:0032755

GO:0032760

GO:0033147

GO:0036211

GO:0042531

GO:0043226

GO:0043425

GO:0043524

GO:0043565

GO:0045597

GO:0045665

GO:0045766

GO:0045944

GO:0046872

GO:0048663

GO:0048665

GO:0048762

GO:0048856

GO:0048863

GO:0048870

GO:0048880

GO:0048935

GO:0048936

GO:0050728

GO:0055010

GO:0060037

GO:0060070

GO:0060379

GO:0060384

GO:0060413

GO:0060913

GO:0060931

GO:0061629

GO:0065003

GO:0071385

GO:0071657

GO:0086091

GO:0090090

GO:0140110

GO:1901258

GO:1990837

GO:1990841

HMNXSV003001258

ILMN_1763390

PH_hs_0000061

TC05000212.hg

U07559_at

g4504736_3p_at

Participates

as an output of

Expression of ISL1 in cardiogenesis (Homo sapiens)

as a component of

This entity regulates

Positively

Synthesis of prepro-Glucose-dependent Insulinotropic Polypeptide (preproGIP) in intestinal K cells (Homo sapiens)

Cross References

RefSeq

NP_002193.2

OpenTargets

ENSG00000016082

HPA

ENSG00000016082-ISL1

GeneCards

P61371

Ensembl

ENSP00000230658, ENSG00000016082, ENST00000230658

PRO

P61371

Pharos - Targets

P61371

Orphanet

23237

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8NB15 ZN511			0.781	7
UniProt:Q969G2 LHX4	1	LHX4 [nucleoplasm] (R-HSA-9010585)	0.667	3
UniProt:Q96PV0 SYNGAP1	1	SYNGAP1 [cytosol] (R-HSA-5658217)	0.623	8
UniProt:Q86U70-2 LDB1			0.556	7
UniProt:P25377 ADH7			0.556	3
UniProt:Q9BWG4 SSBP4			0.547	2